▎ 摘　　要

NOVELTY - A micro RNA-214 inhibitor-degradable material comprises oxidized graphene, polyethylene imine, micro RNA-214 inhibitor, silk fibroin and nanometer hydroxyl apatite, where the micro RNA-214 inhibitor-degradable material having a function of inducing osteogenic differentiation and bone regeneration. USE - Micro RNA-214 inhibitor-degradable material for bone repair (claimed). ADVANTAGE - The degradable material has better osteogenic differentiation function and higher biological activity. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a method for producing a microRNA-214 inhibitor-degradable material, which involves disposing graphene oxide and polyethyleneimine into a solution of a certain concentration, mixing, sonicating and stirring to obtain a graphene oxide-polyethyleneimine complex solution, combining the complex solution with the micro RNA-214 inhibitor in a phosphate buffer solution, vortexing at room temperature and obtaining a graphene oxide-polyethyleneimine complex solution carrying a micro RNA-214 inhibitor after incubation, mixing and stirring the ammonium hydrogen phosphate solution and the calcium chloride solution and centrifuging at room temperature and freeze-drying the obtained precipitate to obtain nano-hydroxyapatite particles, extracting the silk fibroin from the dried silkworm pupa, placing in a lithium bromide solution, dissolving to obtain a silk fibroin solution and collecting by centrifugation, mixing the silk fibroin solution with nano-hydroxyapatite and the graphene oxide-polyethyleneimine-loaded micro-RNA-214 inhibitor complex o and adding to the hole In the plate and obtaining a degradable material having a function of inducing osteogenic differentiation and bone regeneration after dehydration.