• 专利标题:   Preparing nerve conduit, involves co-axially electro spinning multiple rod-like receivers by using first spinning solution and second spinning solution to form tubular layer, and co-axially electro spinning multiple tubular layers by using first and second spinning solutions to form wrapping layer.
  • 专利号:   CN115444976-A
  • 发明人:   QIU Z, CUI M, HU G, WU J, HU Y, ZHU J, HE Z, SONG T, CUI Y
  • 专利权人:   WEIFANG AOJING HEALTH TECHNOLOGY CO LTD, ALLGENS MEDICAL TECHNOLOGY CO LTD
  • 国际专利分类:   A61L027/02, A61L027/18, A61L027/20, A61L027/22, A61L027/24, A61L027/54, A61L027/58, D01D005/00, D01D005/34
  • 专利详细信息:   CN115444976-A 09 Dec 2022 A61L-027/18 202313 Chinese
  • 申请详细信息:   CN115444976-A CN11171020 23 Sep 2022
  • 优先权号:   CN11171020

▎ 摘  要

NOVELTY - Preparing a nerve conduit, involves (a) co-axially electro spinning multiple rod-like receivers by using a first spinning solution and a second spinning solution to form a tubular layer on each of the rod-like receivers, where the tubular layer comprises fibers having a core-shell structure, (b) co-axially electro spinning multiple the tubular layers by using the first and second spinning solutions to form a wrapping layer outside all of the tubular layers, where the coating layer comprises fibers having the core-shell structure, the core of the core-shell structure is formed by a solute of the first spinning solution, the solute of the first spinning solution comprises biological protein, the shell of the core-shell structure is formed by a solute of the second spinning solution, and the solute of the second spinning solution comprises biodegradable polymers, and (c) removing the rod-shaped receiver to obtain a nerve conduit with multiple channels. USE - Method for preparing nerve conduit. ADVANTAGE - The method enables to prepare nerve conduit, which avoids the nerve error and multi-innervation. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a nerve conduit.