• 专利标题:   Preparation of graphene-xanthan gum three-dimensional bracket for repairing spinal cord injury, involves adding reduced graphene oxide into de-ionized water, stirring, and putting it into ultrasonic cleaner for ultrasonic.
  • 专利号:   CN114099783-A
  • 发明人:   GAO G, XUE F, DUAN L
  • 专利权人:   UNIV CHANGCHUN TECHNOLOGY
  • 国际专利分类:   A61L027/44, A61L027/50, A61L027/56
  • 专利详细信息:   CN114099783-A 01 Mar 2022 A61L-027/44 202278 Chinese
  • 申请详细信息:   CN114099783-A CN11286827 02 Nov 2021
  • 优先权号:   CN11286827

▎ 摘  要

NOVELTY - Preparing graphene-xanthan gum three-dimensional porous spinal cord injury repair support involves adding reduced graphene oxide to deionized water, stirring for 1 hour, and then placing it in an ultrasonic cleaner for ultrasonic treatment for 1 hours to form a uniform dispersion solution, adding xanthan gelling agent and reduced graphene dioxide dispersion to de-ionized aqueous water, and stirring for one hour until the xanter gum is completely dissolved, preparing an aluminum trichloride solution with a mass concentration of 10-20 g/l, placing the prepared graphene-Xantergelling agent solution in a polytetrafluoroethylene reaction mold, and placing it into the aluminum tetrachelate solution for 24 hours, washing the obtained hydrogel by a large amount of deionizing water and soaking for 72 hours. USE - Preparation method of graphene-xanthanthan gum three-dimensional bracket for repairing spinal cord injury. Uses include but are not limited to surgery, drug treatment, cell transplantation and stent implantation. ADVANTAGE - The method enables to prepare graphene-xanthan gum three-dimensional porous bracket, which has good biocompatibility, mechanical performance and conductivity matched with spinal cord tissue, and three- dimensional porous internal structure suitable for cell growth, and has good biological compatibility and excellent conductivity. DETAILED DESCRIPTION - Preparing graphene-xanthan gum three-dimensional porous spinal cord injury repair support involves adding reduced graphene oxide to deionized water, stirring for 1 hour, and then placing it in an ultrasonic cleaner for ultrasonic treatment for 1 hours to form a uniform dispersion solution, adding xanthan gelling agent and reduced graphene dioxide dispersion to de-ionized aqueous water, and stirring for one hour until the xanter gum is completely dissolved, preparing an aluminum trichloride solution with a mass concentration of 10-20 g/l, placing the prepared graphene-Xantergelling agent solution in a polytetrafluoroethylene reaction mold, and placing it into the aluminum tetrachelate solution for 24 hours, washing the obtained hydrogel by a large amount of deionizing water and soaking for 72 hours, removing the unreacted aluminium ion, freezing in the refrigerator at minus 70℃and drying by using a freeze drier, finally obtaining the graphene-xanthan gum three-dimensional porous spinal cord repairing bracket.