• 专利标题:   Woven nanofiber yarn and hydrogel composite dressing useful as wound pressure monitoring dressing, network-shaped nanofiber yarn 3D scaffold is loaded inside hydrogel, hydrogel includes quaternized carboxymethyl chitosan and dopamine-grafted oxidized dextran.
  • 专利号:   CN115006580-A, CN115006580-B
  • 发明人:   DAI S, CUI J, YU J, WANG X, LI F, ZENG Y, WANG Q, QIU W, WU D
  • 专利权人:   AOMEI MEDICAL PROD CO LTD, UNIV DONGHUA
  • 国际专利分类:   A61B005/00, A61B005/11, A61L015/18, A61L015/24, A61L015/28, A61L015/42, A61L015/44, A61L015/46, C08B037/08, D06M101/28, D06M101/40, D06M015/03
  • 专利详细信息:   CN115006580-A 06 Sep 2022 A61L-015/24 202297 Chinese
  • 申请详细信息:   CN115006580-A CN10081988 24 Jan 2022
  • 优先权号:   CN10081988

▎ 摘  要

NOVELTY - Woven nanofiber yarn and hydrogel composite dressing, is claimed. A network-shaped nanofiber yarn 3D scaffold is loaded inside the hydrogel, the hydrogel includes quaternized carboxymethyl chitosan and dopamine-grafted oxidized dextran, the network-shaped nanofiber yarn 3D scaffold includes polyacrylonitrile and reduced graphene oxide. USE - The composite dressing is useful as wound pressure monitoring dressing (claimed). ADVANTAGE - The composite dressing: has function of monitoring the pressure at the wound; and can actively prevents the occurrence of pressure ulcers, is of great significance to reduce the incidence of pressure ulcers in hospitalized bedridden patients, saves medical resources, improves the quality of life of bedridden patients, and improves the quality of nursing. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for preparing the woven nanofiber yarn and hydrogel composite dressing comprising (1) blending polyacrylonitrile and reduced graphene oxide to prepare nanofiber yarns, and weaving them to obtain a 3D scaffold with network structure; and (2) dropping the mixed solution of quaternized carboxymethyl chitosan and dopamine-grafted oxidized dextran on the 3D scaffold with network structure obtained in step (1), and Schiff base crosslinking.