• 专利标题:   Nanodevice i.e. graphene nanopore transistor device, for identifying and differentiating biomolecules in e.g. DNA sequencing application, has graphene layer wired to metal pads to form transistor in which transistor current is modulated.
  • 专利号:   US2013270521-A1, US9758821-B2
  • 发明人:   PENG H, STOLOVITZKY G A, ZHU W
  • 专利权人:   INT BUSINESS MACHINES CORP, INT BUSINESS MACHINES CORP, PENG H, STOLOVITZKY G A, ZHU W
  • 国际专利分类:   B82Y099/00, H01L029/775, B82Y005/00, C12Q001/68, G01N027/62, G01N033/487
  • 专利详细信息:   US2013270521-A1 17 Oct 2013 H01L-029/775 201370 Pages: 20 English
  • 申请详细信息:   US2013270521-A1 US448509 17 Apr 2012
  • 优先权号:   US448509

▎ 摘  要

NOVELTY - The nanodevice i.e. graphene nanopore transistor device (100), has a reservoir separated into two parts by a free-standing membrane (155). A nanopore (110) is formed through the membrane and connects the parts of the reservoir. The nanopore and the parts of the reservoir are filled with ionic buffer. The membrane comprises a graphene layer (104) and insulating layers (102, 106), where the graphene layer is wired to metal pads (105a, 105b) to form a graphene transistor in which transistor current flowing through the graphene transistor is modulated by charges passing through the nanopore. USE - Nanodevice i.e. graphene nanopore transistor device, for identifying and differentiating biomolecules in DNA and RNA sequencing applications. Can also be used for analyzing protein. ADVANTAGE - The nanodevice identifies and differentiates molecules driven through a nanopore one by one, where each individual molecule can modulate the current through the graphene transistor, thus allowing molecular detection with single molecule accuracy. DETAILED DESCRIPTION - The ionic buffer is an electrical conducting fluid of ions. DESCRIPTION OF DRAWING(S) - The drawing shows a cross-sectional view of a graphene nanopore transistor device. Graphene nanopore transistor device (100) Insulating layers (102, 106) Graphene layer (104) Metal pads (105a, 105b) Nanopore (110) Free-standing membrane (155)