▎ 摘　　要

NOVELTY - Preparing tumor drug targeting carrier comprises e.g. carrying out preparation of high-purity graphene oxide, stirring, centrifuging, performing hydrolysis and polymerization, performing polycondensation reaction, distilling polyaluminum ferric chloride solution, setting milling time, collecting out ball milled product, heating, setting heating temperature, stirring and stop heating, allowing to stand, performing high-speed stirring, setting rotating speed, setting drying temperature, grinding solid, ultrasonically dispersing to disperse mixed solution, drying dispersion, placing obtained solid substance in calcination furnace, filling with argon gas as protective gas for heating and calcination, calcining sintering beam, setting cooling rate to 50-80 degrees C/minutes for cooling, lowering temperature to room temperature and opening calciner to obtain calcined material, grinding calcined material to immediately obtain a granular tumor drug targeting carrier. USE - The method is useful in preparing tumor drug targeting carrier for preparation of antitumor drug (claimed). ADVANTAGE - The carrier: has specific affinity, no obvious cytotoxicity to normal cells and has high safety; contains ginsenoside rh2, which achieves consistent pain in tumor area; contains medicine composition, which enhances efficacy of tumor treatment and reduces side effects of treatment; and also has better tumor treatment effect. DETAILED DESCRIPTION - Preparing tumor drug targeting carrier comprises (i) carrying out preparation of high-purity graphene oxide, placing prepared graphene oxide in deionized water for ultrasonic dispersion to obtain a graphene oxide dispersion, where the frequency of ultrasonic dispersion is 45-55 kHz, and the time of ultrasonic dispersion is 5-8 minutes, add ammonium bicarbonate solution to graphene oxide dispersion, thoroughly stirring, and centrifuging to remove excess water to obtain graphene oxide hydrogel, (ii) adding sodium hydroxide solution dropwise to aluminum chloride solution at rate of 3-5 ml/minutes to perform hydrolysis and polymerization to obtain trivalent aluminum hydroxy compound solution, adding ferric chloride solution, sodium hypochlorite solution and sodium hydroxide solution to trivalent aluminum hydroxy compound solution in sequence to perform polycondensation reaction to obtain polyaluminum ferric chloride solution, distilling polyaluminum ferric chloride solution under reduced pressure to recover solvent to obtain polyaluminum ferric chloride, (iii) placing prepared polyaluminum iron chloride particles in a ball milling device, adding ethanol solution with a mass concentration of 75% to ball milling device, using zirconium balls as ball milling medium, setting milling time to 20-45 minutes for ball milling, collecting out ball milled product, heating to remove ethanol, and obtaining nano-scale polyaluminum iron chloride particles, (iv) placing graphene oxide hydrogel in heating device and setting heating temperature to 90 degrees C to 120 degrees C for heating, when the actual temperature of the graphene oxide hydrogel is heated to 90 degrees C, adding nano-scale polyaluminum iron chloride particles, stirring and stop heating, allowing to stand still to less than or equal to 50 degrees C, adding single strand of deoxyribonucleic acid to obtain mixture, placing mixture in stirring device and performing high-speed stirring to complete loading of deoxyribonucleic acid single strands to obtain carrier mixture, (v) placing carrier mixture in centrifuge, setting rotating speed to 300-400 revolutions/minute for 8-12 minutes centrifugation, keeping solid matter and using phosphate buffer saline buffer to wash solid matter, placing cleaned solid substance in drying box, setting drying temperature to 60-95 degrees C and drying time to 15-25 minutes for drying, and obtaining solid with water content of less than or equal to 2.5%, grinding solid to obtain carrier particles, (vi) adding carrier particles to phosphate buffer, adding dispersing agent, and uniformly stirring, adding carrier additives to obtain mixed solution, using ultrasonic dispersion to disperse mixed solution, and adding deionized water during dispersion until uniform dispersion is obtained, and (vii) drying dispersion to obtain solid substance, placing obtained solid substance in calcination furnace, filling with argon gas as protective gas for heating and calcination, calcining sintering beam, setting cooling rate to 50-80 degrees C/minutes for cooling, lowering temperature to room temperature and opening calciner to obtain calcined material, grinding calcined material to immediately obtain a granular tumor drug targeting carrier. An INDEPENDENT CLAIM is also included for tumor drug targeting carrier, comprising 1-2 pts. wt. single-stranded deoxyribonucleic acid, 6-8 pts. wt. graphene oxide hydrosol, 4-5 pts. wt. nano-scale polymeric aluminum iron chloride particles, 5-8 pts. wt. phosphate buffer, 1-3 pts. wt. dispersant, 22-4 pts. wt. ginsenoside rh, 2-3 pts. wt. medicine composition, and 20-50 pts. wt. deionized water. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic representation of flow chart for preparing tumor drug targeting carrier. (Drawing includes non-English language text)