▎ 摘　　要

NOVELTY - Preparation of electrochemical sensor involves (s1) dissolving cerium nitrate or cerium nitrate hexahydrate and trimesic acid in ethanol/deionized water mixed solvent respectively, stirring to form metal solution and organic ligand solution respectively, and washing and drying by ethanol to obtain white solid powder, (s2) placing white solid powder in ark, placing in tube furnace, and pyrolyzing the ark in oxygen-free environment to obtain black solid powder, (s3) immersing black solid powder in acid solution for acidification, cleaning and drying to obtain hydroxide-cerium oxide-carbon, (s4) preparing hydroxide-cerium oxide-carbon/reduced graphene oxide-gold composite suspension, taking the nano-gold particles graphene to disperse in distilled water to form uniform suspension, and uniformly mixing the two uniform suspensions to obtain a composite suspension, and (s5) dripping the composite suspension on the surface of a clean glassy carbon electrode, and drying. USE - Preparation of electrochemical sensor based on cerium-MOF derived hydroxide-cerium oxide-carbon/reduced graphene oxide-gold/modified glassy carbon electrode used for measuring paracetamol concentration (all claimed). ADVANTAGE - The sensor has high detection speed, convenience in operation, low cost and real-time monitoring. The paracetamol sensor has a linear range of 0.05-20 μM, detection limit of 0.02 μM (signal-to-noise ratio is 3), and in the presence of ascorbic acid, citric acid, dopamine, p-chlorophenol and other interfering substances, will not interfere with the detection of paracetamol, wide linear range and low detection limit, good selectivity, and excellent recovery for detection of paracetamol in real environmental samples. DETAILED DESCRIPTION - Preparation of electrochemical sensor based on cerium-MOF derived hydroxide-cerium oxide-carbon/reduced graphene oxide (rGO)-gold/modified glassy carbon electrode involves (s1) dissolving cerium nitrate or cerium nitrate hexahydrate and trimesic acid in ethanol/deionized water mixed solvent respectively, stirring to form metal solution and organic ligand solution respectively, and slowly pouring metal solution in organic ligand solution, stirring to form a white precipitate, centrifugally collecting the white precipitate, and washing and drying by ethanol to obtain white solid powder, (s2) placing white solid powder in ark, and placing the ark in tube furnace, and heating and pyrolyzing the ark in oxygen-free environment to obtain black solid powder, (s3) immersing black solid powder in acid solution for acidification, performing suction filtration and separation by using vacuum filter, cleaning and drying to obtain hydroxide-cerium oxide-carbon, (s4) preparing hydroxide-cerium oxide-carbon/reduced graphene oxide-gold composite suspension, dispersing hydroxide-cerium oxide-carbon in uniform suspension in distilled water, taking the nano-gold particles graphene to disperse in distilled water to form uniform suspension, and uniformly mixing the two uniform suspensions to obtain a composite suspension, and (s5) dripping the composite suspension on the surface of a clean glassy carbon electrode, and drying. An INDEPENDENT CLAIM is included for electrochemical sensor based on cerium-MOF derived hydroxide-cerium oxide-carbon/reduced graphene oxide-gold/modified glassy carbon electrode, which is working electrode, graphite electrode or platinum wire electrode as counter electrode, and silver/silver chloride electrode as reference electrode. The potential range is 0.1-0.7 V, the scanning amplitude is 50 mV, the pulse width is 200ms, and the environmental solution is phosphate-buffered saline buffer solution with pH is 6.8-7.2.