• 专利标题:   Preparation of graphene pediatric paste used for reducing fever, involves taking raw materials including holly bark and mint, crushing, soaking in ethanol solution, soaking, combining filtrates, concentrating, clarifying and decolorizing.
  • 专利号:   CN109010773-A
  • 发明人:   ZHAO L, TANG N, SONG C, ZHONG Y, WANG X, YU P, LI J
  • 专利权人:   UNIV GUANGXI CHINESE MEDICINE
  • 国际专利分类:   A61K036/9068, A61K009/06, A61K047/04, A61P029/00
  • 专利详细信息:   CN109010773-A 18 Dec 2018 A61K-036/9068 201920 Pages: 8 Chinese
  • 申请详细信息:   CN109010773-A CN11113235 25 Sep 2018
  • 优先权号:   CN11113235

▎ 摘  要

NOVELTY - Preparation of graphene pediatric paste comprises taking 15-20 pts. wt. holly bark, 15-20 pts. wt. mint, 10-15 pts. wt. elder flower, 5-10 pts. wt. ginger, 2-5 pts. wt. Perilla, crushing, soaking in 40-70% ethanol solution for 3 hours, soaking for 1-3 times, combining filtrates, concentrating under reduced pressure, clarifying, decolorizing, eluting with AB-8 macroporous resin using 30-50% ethanol, washing under reduced pressure, drying to obtain Chinese herbal extract, dissolving 200 mg graphene powder in 1 L aqueous solution of Chinese herbal medicine extract, ultrasonically dispersing for 1 hour to obtain graphene solution, stirring, adding 1 mol/L gelatin solution, stirring for 1 hour, mixing, standing for 24 hours, removing bubbles to obtain graphene-gelatin drug-loaded hydrogel, uniformly stirring, pouring into mold and placing in refrigerator at 0-4 degrees C for 24-48 hours. USE - Method for preparing graphene pediatric paste used for reducing fever (claimed). ADVANTAGE - The product is convenient for the patient to absorb; and achieves good antipyretic treatment effect.