▎ 摘　　要

NOVELTY - Preparing photothermal-thermoelectric integrated anti-tumor implant involves: (a) in-situ growing bismuth sulfide on the surface of graphene oxide by utilizing the chelation effect of oxygen-containing functional groups of the graphene oxide to obtain a graphene oxide-bismuth sulfide nano composite material; (b) dissolving the graphene oxide-bismuth sulfide nano composite material in a mixed solvent C to obtain a mixed solution D; (c) dissolving polycaprolactone powder in the mixed solvent C to obtain polycaprolactone mixed solution E; mixing the mixed solution D and the polycaprolactone mixed solution E to obtain an electrostatic spinning solution F; and (d) preparing the electrostatic spinning solution F by using an electrostatic spinning process to obtain an anti-tumor implant with a required shape, inactivating the tumor by using graphene oxide in the anti-tumor implant through a photo-thermal effect. USE - Method for preparing photothermal-thermoelectric integrated anti-tumor implant. ADVANTAGE - The implant synergistically inactivates the tumors by releasing active oxygen, and avoids the heat resistance of the photothermal therapy and improves the anti-tumor treatment effect. DETAILED DESCRIPTION - Preparing photothermal-thermoelectric integrated anti-tumor implant involves: (a) in-situ growing bismuth sulfide on the surface of graphene oxide by utilizing the chelation effect of oxygen-containing functional groups of the graphene oxide to obtain a graphene oxide-bismuth sulfide nano composite material; (b) dissolving the graphene oxide-bismuth sulfide nano composite material in a mixed solvent C to obtain a mixed solution D; (c) dissolving polycaprolactone powder in the mixed solvent C to obtain polycaprolactone mixed solution E; mixing the mixed solution D and the polycaprolactone mixed solution E to obtain an electrostatic spinning solution F; and (d) preparing the electrostatic spinning solution F by using an electrostatic spinning process to obtain an anti-tumor implant with a required shape, inactivating the tumor by using graphene oxide in the anti-tumor implant through a photo-thermal effect, converting the temperature change of the dispersed bismuth sulfide in the photo-thermal effect process into a pyroelectric charge, and synergistically inactivating the tumor by releasing active oxygen.