▎ 摘　　要

NOVELTY - Graphene nanopore sensor comprises a substantially bare, single-layer graphene membrane (14) having a nanopore (12) extending through a thickness of the graphene membrane from a first graphene membrane surface to a second graphene membrane surface opposite first graphene membrane surface, a connection from first graphene membrane surface to a first reservoir to provide at the first graphene membrane surface, and a species in an ionic solution to nanopore. USE - Graphene nanopore sensor for detecting molecule by measurement of ionic flow. ADVANTAGE - The graphene nanopore sensor enables high-sensitivity molecular detection and analysis, and overcomes sensitivity and resolution limitation of conventional sensor. DETAILED DESCRIPTION - Graphene nanopore sensor comprises a substantially bare, single-layer graphene membrane having a nanopore extending through a thickness of the graphene membrane from a first graphene membrane surface to a second graphene membrane surface opposite first graphene membrane surface, a connection from first graphene membrane surface to a first reservoir to provide at the first graphene membrane surface, and a species in an ionic solution to nanopore, a connection from the second graphene membrane surface to a second reservoir to collect species and ionic solution after translocation of species and ionic solution through the nanopore from first graphene membrane surface to the second graphene membrane surface, and an electrical circuit connected on opposite sides of the nanopore to measure flow of ionic current through the nanopore in the graphene membrane. INDEPENDENT CLAIMS are included for: (1) a nanopore sensor, which comprises a solid state membrane having a thickness which is between a first membrane surface and a second membrane surface opposite the first membrane surface that is less than 1nm, a nanopore extends through the membrane thickness between first and second membrane surfaces and having a diameter that is more than the membrane thickness, a connection from first membrane surface to a first reservoir to provide species in an ionic solution to the nanopore at the first membrane surface, a connection from second membrane surface to a second reservoir to collect the species and ionic solution after translocation of species and ionic solution through the nanopore from first membrane surface to the second membrane surface, and an electrical circuit connected to monitor translocation of species in the ionic solution through nanopore in the solid state membrane; and (2) a method for evaluating a polymer molecule, which involves providing an ionic solution a polymer molecule to be evaluated; translocating the polymer molecule in the ionic solution through a nanopore in a substantially bare, single-layer graphene membrane from a first graphene membrane surface to a second graphene mernbrane surface opposite the first graphene surface; and monitoring the flow of ionic current through the nanopore in graphene membrane. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of graphene nanopore sensor for detecting molecule by measurement of ionic flow. Nanopore (12) Single-layer graphene membrane (14) Support frame (16) Support substrate (18) Voltage bias (24)