▎ 摘　　要

NOVELTY - Biological field-effect transistor (BioFET) (100) comprises source region (106) and drain region (108) formed in a substrate, an insulating layer disposed on a surface of the substrate, a gate disposed on the insulating layer (110) and extending between the source and drain regions, a well region (140) containing an electrolyte solution configured to retain an analyte, a three-dimensional (3D) graphene layer forming a channel region in the substrate, the 3D graphene layer biofunctionalized with a molecular recognition element configured to alter one or more electrical properties of the 3D graphene layer in response to exposure of the molecular recognition element to the analyte, and a passivation layer configured to prevent the electrolyte solution from contacting the source and drain. USE - Biological field-effect transistor (BioFET) for detecting a presence of analytes in an environment ADVANTAGE - The biological field-effect transistor decreases their ability to accurately detect the presence and concentration levels of analytes. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of a biosensor field-effect transistor (BioFET). Biological field-effect transistor (100) Source region (106) Drain region (108) Insulating layer (110) Well region (140)