• 专利标题:   Terahertz device for capturing and detecting circulating tumor cells, comprises a graphene film coated on the silica substrate, and a ring-shaped area is used to capture circulating tumor cells and to detect captured circulating tumor cells.
  • 专利号:   CN111610155-A
  • 发明人:   ZHANG L, SHEN Z, CHEN X, XU Y, HAN D, WANG Z, LI S
  • 专利权人:   UNIV XIAN JIAOTONG
  • 国际专利分类:   G01N021/03, G01N021/25
  • 专利详细信息:   CN111610155-A 01 Sep 2020 G01N-021/25 202075 Pages: 10 Chinese
  • 申请详细信息:   CN111610155-A CN10491906 02 Jun 2020
  • 优先权号:   CN10491906

▎ 摘  要

NOVELTY - The terahertz device comprises a graphene film coated on the silica substrate, and the graphene film is etched with multiple ring-shaped nanogaps that are arranged in an array to form a periodic ring-shaped nanogap array. The ring-shaped area of each ring-shaped nanogap is a capture and detection area, which is used to capture the circulating tumor cells and to detect the captured circulating tumor cells. The periodic ring-shaped nanogap array obtains a near-field capturing force by localizing the terahertz wave in the capturing area, and the detection of the captured circulating tumor cells is performed by detecting the amount of resonant frequency shift of the device. USE - Terahertz device for capturing and detecting circulating tumor cells. ADVANTAGE - The terahertz device uses the graphene coaxial holes to form terahertz plasmon tweezers to achieve near-field capture of tumor cells, and combines the tunable optical properties of graphene to meet the requirements for capturing performance of tumor cells of different sizes and different refractive indices, and achieves specific capture of circulating tumor cells. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing the terahertz device. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of a terahertz device. (Drawing includes non-English language text).