• 专利标题:   Method of preparing graphene oxide protein-matrix involves connecting fluid at nozzle with reservoir of disordered protein and delivering through nozzle to reservoir that comprise GO and controlling nozzle by computer.
  • 专利号:   WO2020058456-A1
  • 发明人:   WU Y, WANG W, CHAVARRIA A M
  • 专利权人:   UNIV QUEEN MARY LONDON
  • 国际专利分类:   A61L027/08, A61L027/22, A61L027/38, A61L027/50, A61L027/54
  • 专利详细信息:   WO2020058456-A1 26 Mar 2020 A61L-027/08 202032 Pages: 121 English
  • 申请详细信息:   WO2020058456-A1 WOEP075264 19 Sep 2019
  • 优先权号:   GB015285

▎ 摘  要

NOVELTY - The method involves admixing an aqueous solution of a disordered protein with an aqueous solution of a graphene oxide. The disordered protein is comprised of opposite charge to the graphene oxide. The graphene oxide protein-matrix is formed as a three- dimensional structure (3D) with a lumen that is defined by a membrane with an inner and outer surface. A reservoir is contained with the aqueous solution of disordered protein. A nozzle in the fluid is connected with the reservoir of disordered protein solution. The disordered protein solution is delivered through the nozzle to a reservoir that comprise the graphene oxide and the nozzle is controlled by a computer. USE - Method of preparing a graphene oxide protein-matrix (claimed). ADVANTAGE - The overall length and the molecular weight of a polypeptide is reduced. The co-assembly in the presence of cells is enabled without affecting the structural integrity of the generated membrane. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a kit for preparing a graphene oxide protein-matrix. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view illustrating molecular building blocks and rationale for co-assembly.