▎ 摘 要
NOVELTY - A graphene nanomesh (GNM) based charge sensor comprises a GNM with a patterned array of multiple holes created by generating multiple holes in graphene in a periodic way, where the passivated edge of each of the multiple holes of the GNM is functionalized with a chemical compound that facilitates chemical binding of a receptor of a target molecule to the edge of the multiple holes, allowing the target molecule to bind to the receptor, causing a charge to be transferred to the GNM. USE - The GNM based charge sensor is used for detecting a target molecule. ADVANTAGE - Provided is a functionalized GNM system that provides a low limit of detection and a high resistance to non-specific binding.