• 专利标题:   Graphene nanomesh (GNM) based charge sensor for detecting a target molecule comprises a GNM with a patterned array of multiple holes each having a passivated edge functionalized with a chemical compound that facilitates chemical binding.
  • 专利号:   US2015276726-A1, US9766229-B2
  • 发明人:   AFZALIARDAKANI A, HAN S, KASRY A, MAAROUF A, MARTYNA G J, NISTOR R, TSAI H
  • 专利权人:   INT BUSINESS MACHINES CORP, EGYPT NANOTECHNOLOGIES CENT EGNC
  • 国际专利分类:   G01N033/53, G01N033/543, G01N033/551, B82Y030/00, B82Y040/00, C01B031/04, C40B060/10
  • 专利详细信息:   US2015276726-A1 01 Oct 2015 G01N-033/53 201569 Pages: 10 English
  • 申请详细信息:   US2015276726-A1 US699318 29 Apr 2015
  • 优先权号:   US310194, US699318

▎ 摘  要

NOVELTY - A graphene nanomesh (GNM) based charge sensor comprises a GNM with a patterned array of multiple holes created by generating multiple holes in graphene in a periodic way, where the passivated edge of each of the multiple holes of the GNM is functionalized with a chemical compound that facilitates chemical binding of a receptor of a target molecule to the edge of the multiple holes, allowing the target molecule to bind to the receptor, causing a charge to be transferred to the GNM. USE - The GNM based charge sensor is used for detecting a target molecule. ADVANTAGE - Provided is a functionalized GNM system that provides a low limit of detection and a high resistance to non-specific binding.