▎ 摘　　要

NOVELTY - The biosensor comprises a substrate (1), where the surface of the substrate is provided with a layer of piezoelectric film (2). A surface of an interdigital resonator (4) is connected with two interdigital transducers (3). The interdigital resonance is located between the two inter digital resonators. A silicon dioxide film (5) is provided on the surface, and a single-layer graphene (6) is attached to the surface. The nucleicacid aptamer (8) is anchored on the graphene surface by a linking molecule (7) containing an aromatic ring structure. USE - Nucleic acid aptamer-based flexible surface acoustic wave biosensor used in micro-nano manufacturing technology and flexible electronic technology for detecting biological markers. ADVANTAGE - The nucleic acid aptamer-based flexible acoustic surface wave graphene biosensor is capable of realizing fast detection of biological markers, which can cope with sweat, tears, and saliva non-invasive sampling detection scene, high integration degree, good portability, and less sample requirement. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a method for preparing a nucleic acid aptamer-based flexible surface acoustic wave biosensor. DESCRIPTION OF DRAWING(S) - The drawing shows a structure schematic diagram of the nucleic acid aptamer-based flexible surface acoustic wave biosensor. Flexible substrate (1) Piezoelectric film (2) Interdigital transducer (3) Interdigital resonator (4) Silicon dioxide film (5) Single-layer graphene (6) Linking molecule containing aromatic ring structure (7) Nucleic acid aptamer (8)