▎ 摘 要
NOVELTY - A preparation method of fluorescent graphene oxide nano-membrane comprises (S1) crushing large-diameter graphene oxide solution is ultrasonically, and after two consecutive ultrasonic waves, a small-diameter graphene oxide solution is obtained, (S2) adding fluorescein isothiocyanate powder into the small-diameter graphene oxide solution and performing ultrasonic crushing, (S3) placing the small-diameter graphene oxide solution containing crushed fluorescein isothiocyanate powder obtained in step (S2) in a dialysis membrane, and adding deionized water for dialysis until no salt is precipitated, and (S4) collecting the dialysis product, placing it on the smooth surface of the polyethylene terephthalate film, and drying it with closed light to obtain a fluorescent graphene oxide nano-membrane. USE - The method is used for preparing fluorescent graphene oxide nano-membrane, which is used as a material in drug delivery systems, used in antifungal agents, antiviral agents, antibacterial agents, condom coating agents, and sperm fertilization enhancers, and used in the treatment of ectopic pregnancy, trophoblastic disease, endometriosis, uterine fibroids and assisted reproduction (all claimed). ADVANTAGE - The fluorescent graphene oxide nano-membrane prepared by the above-mentioned method lays a foundation for the research of graphene oxide in the drug-carrying system and in the application of reproduction. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for verifying the degradability of the fluorescent graphene oxide nano-membrane comprising (S11) subjecting the obtained fluorescent graphene oxide nanofilm to film Fourier transform infrared spectrum characterization and atomic force microscopy (AFM) measurement, (S12) cutting the fluorescent graphene nano-membrane to a size of 0.5 × 0.5 cm, and embed it under the skin of C57/B6 mice, and (S13) one week later, the degradation of the fluorescent graphene oxide nano-membrane and the fluorescence expression of fluorescein isothiocyanate in mouse tissues were detected.