• 专利标题:   Method for preparing electrochemical sensor based on DNA aptamer for dopamine detection, involves synthesizing copper aluminum oxide/reduction graphene-tetraethylenepentaammonia composite material by solvent thermal method.
  • 专利号:   CN116046868-A
  • 发明人:   YIN S, ZHU J, ZHAO F, CAO L, XIAO H, LI S, WEI S, REN H, CHEN Z
  • 专利权人:   UNIV GUILIN ELECTRONIC TECHNOLOGY
  • 国际专利分类:   G01N027/327, G01N027/48
  • 专利详细信息:   CN116046868-A 02 May 2023 G01N-027/327 202350 Chinese
  • 申请详细信息:   CN116046868-A CN11463174 22 Nov 2022
  • 优先权号:   CN11463174

▎ 摘  要

NOVELTY - The method involves synthesizing copper aluminum oxide (CuAlO2)/reduction graphene-tetraethylenepentaammonia (rGO-TEPA) composite material by solvent thermal method. The CuAlO2/rGO-TEPA composite material is taken as electrode substrate material. Electrodepositing precess of gold-platinum nanoparticles (AuPtNPs) is performed. A dopamine-dopamine (DA) electrochemical sensor is prepared by using a DNA aptamer. Bovine serum albumin (BSA) is used to seal an active site of a non-adsorbed adenosine aptamer on a working electrode for preparing the DA electrochemical sensor. USE - Method for preparing an electrochemical sensor based on DNA aptamer for dopamine detection. ADVANTAGE - The method enables preparing the electrochemical sensor with high sensitivity and strong anti-interference detection of DA in human body liquid, thus specifically recognizing the DA, widening the detection range, and improving the sensitivity of detection. DESCRIPTION OF DRAWING(S) - The drawing shows a flow diagram illustrating an electrochemical sensor preparation method for dopamine detection based on DNA aptamer. (Drawing includes non-English language text).