▎ 摘　　要

NOVELTY - Preparing implantable gel photoelectrode involves preparing 0.5-20 wt.% high molecular polymer solution as a skin layer spinning solution, obtaining 10-90 wt.% gel monomer solution as first core layer spinning solution, obtaining 0.5-10 wt.% carbon-based hybrid spinning solution as second core layer spinning solution, extruding skin layer spinning solution, first core layer spinning solution and second core layer spinning solution into water bath of coagulation bath through the dual-core spinning nozzle, and setting a ultraviolet point light source at a distance of 1-100 mm from spinneret, solidifying skin layer spinning solution and second core layer spinning solution in coagulation bath, and passing first core layer spinning solution in ultraviolet curing zone and then solidifying, molding to obtain primary hydrogel fibers, then collecting by drying and winding. USE - Method used for preparing implantable gel photoelectrode. ADVANTAGE - The preparation method has benefits of continuous, controllable diameter and adjustable mechanical properties, and the prepared implantable gel photoelectrode has excellent light-conducting properties, electrical conductivity properties and mechanical properties that can be highly adapted to soft tissues. The preparation method is suitable for preparing photoelectrodes, and the prepared photoelectrodes are suitable for optogenetics. DETAILED DESCRIPTION - Preparing implantable gel photoelectrode involves preparing 0.5-20 wt.% high molecular polymer solution as a skin layer spinning solution, obtaining 10-90 wt.% gel monomer solution as first core layer spinning solution, obtaining 0.5-10 wt.% carbon-based hybrid spinning solution as second core layer spinning solution, extruding skin layer spinning solution, first core layer spinning solution and second core layer spinning solution into water bath of coagulation bath through the dual-core spinning nozzle, and setting a ultraviolet point light source at a distance of 1-100 mm from spinneret, solidifying skin layer spinning solution and second core layer spinning solution in coagulation bath, and passing first core layer spinning solution in ultraviolet curing zone and then solidifying, molding to obtain primary hydrogel fibers, then collecting by drying and winding, and after being reduced by a reducing agent, obtaining an implantable gel photoelectrode. The high molecular polymer is a polymer that can be wet-spun. The gel monomer solution components include a matrix component, a hydrophilic component, an initiator component and water. The matrix component is a bifunctional polyethylene glycol derivative. The hydrophilic component is acrylamide derivative. The initiator component is a photoinitiator, and the carbon-based hybrid spinning solution includes a matrix carbon-based material, conductive nano-filler and water, and the matrix carbon-based material adopts one of graphene oxide, graphene and carbon nanotubes. The conductive nanofiller is one of conductive carbon black, Mxene and silver nanowires. The ratio of matrix carbon-based material and conductive nanofiller is 0.1-1:0-0.9.