• 专利标题:   Reduced graphene oxide used as e.g. implant material for gene delivery, comprises graft copolymer(s) comprising monomer(s) and macromonomer(s).
  • 专利号:   WO2018088978-A1, TR201616033-A
  • 发明人:   YUKSEL DURMAZ Y, DEMIREL E, DURMAZ Y Y
  • 专利权人:   UNIV ISTANBUL MEDIPOL T C
  • 国际专利分类:   A61L027/30, A61L027/34, C01B032/198
  • 专利详细信息:   WO2018088978-A1 17 May 2018 A61L-027/30 201837 Pages: 39 English
  • 申请详细信息:   WO2018088978-A1 WOTR000077 05 Jul 2017
  • 优先权号:   TR016033

▎ 摘  要

NOVELTY - A reduced graphene oxide comprises graft copolymer(s) (1) comprising monomer(s) and macromonomer(s). USE - Reduced graphene oxide is used as implant material for gene delivery, drug delivery and release, and as dual drug that is both therapeutic and genetic carrier, or by loading an anti-cancer drug, or for drug delivery to brain (all claimed). ADVANTAGE - The biocompatible reduced graphene oxide has excellent durability and rigidity, and no toxic effects. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for graphene oxide coating method. DESCRIPTION OF DRAWING(S) - The drawing shows a molecular view of the graft copolymer. Graft copolymer (1) Polyethylene glycol (11) Methyl methacrylate (12) Pyrenemethyl methacrylate (13)