• 专利标题:   Kit used for screening and diagnosing cancer e.g. eye choroid melanoma and cervical cancer, comprises solution A comprising cyclotriphosphazene doped graphene quantum dots, and solution B comprising phosphate buffer saline buffer solution.
  • 专利号:   CN111721933-A
  • 发明人:   DING G, YANG S, XU A
  • 专利权人:   SHANGHAI INST MICROSYSTEM INFORMATION
  • 国际专利分类:   G01N033/574, G01N033/58
  • 专利详细信息:   CN111721933-A 29 Sep 2020 G01N-033/574 202088 Pages: 11 Chinese
  • 申请详细信息:   CN111721933-A CN10876709 17 Sep 2019
  • 优先权号:   CN10876709

▎ 摘  要

NOVELTY - Kit comprises a solution A comprising cyclotriphosphazene doped graphene quantum dots, and a solution B comprising a phosphate buffer saline (PBS) buffer solution. USE - The kit is useful for screening and diagnosing cancer chosen from choroidal melanoma, cervical cancer, choroidal malignant melanoma, thyroid cancer, gastric cancer, acute myelogenous leukemia, breast cancer or kidney cancer (all claimed). ADVANTAGE - The kit screens and ensures diagnosis of cancer in a quick, simple, and cost-effective manner at an early stage and with higher ROS levels, high sensitivity, high specificity and reproducibility, provides very stable fluorescent labeling function for tumor cells, and has high targeting ability and high recognition rate. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for method for detecting tumor cell, which involves providing a kit and a blood sample, anticoagulating and centrifuging the blood sample to obtain a first precipitate, adding solution B to resuspend the first precipitate to obtain a first resuspension, adding solution A, incubating to obtain a mixture, centrifuging the mixture to obtain a second precipitate, adding solution B to resuspend the second precipitate to obtain a second resuspension, and detecting the fluorescence intensity of the second resuspension.