• 专利标题:   Measuring activity of DNA methyltransferase used e.g. as potential cancer biomarker, comprises e.g. preparing carboxylated cadmium telluride quantum dots and cadmium telluride DNA network structure, pre-treating gold electrode, preparing photoelectrochemical biological sensor, and detecting.
  • 专利号:   CN113533477-A
  • 发明人:   WU C, LIU F, LI C, ZHU C, DENG J, WANG L, FANG L, HUANG H, LIU H, LI Y, ZHU Q, ZHENG J
  • 专利权人:   UNIV PLA ARMY MEDICAL
  • 国际专利分类:   G01N027/26, G01N027/327
  • 专利详细信息:   CN113533477-A 22 Oct 2021 G01N-027/327 202224 Chinese
  • 申请详细信息:   CN113533477-A CN10931159 13 Aug 2021
  • 优先权号:   CN10931159

▎ 摘  要

NOVELTY - Measuring activity of DNA methyltransferase comprises preparing reduced graphene oxide cadmium sulfide (RGOcdS): manganese nanoparticle (MnNPs), preparing carboxylated cadmium telluride quantum dots (CdTe QDs) and cadmium telluride (CdTe) DNA network structure, pre-treating gold electrode, preparing photoelectrochemical (PEC) biological sensor, and detecting PEC signal response detection. USE - The method is useful for measuring activity of DNA methyltransferase (claimed) which is used as a potential cancer biomarker and drug action target in cancer treatment. ADVANTAGE - The method is simple to operate, does not need complex and expensive instrument or complex signal mark, and provides ultra-sensitive detection of methyltransferase MTase. DESCRIPTION OF DRAWING(S) - The drawing shows a flow chart illustrating the method for measuring activity of DNA methyltransferase as a potential cancer biomarker and drug action target in cancer treatment (Drawing includes non-English language text).