• 专利标题:   Preparing composite piezoelectric film for inducing bone regeneration from bone defects in context of chronic inflammation, comprises using solvent casting method to form film, which is treated under corona polarization.
  • 专利号:   CN114796601-A, CN114796601-B
  • 发明人:   PENG C, CHU Y, SHU Z, ZHANG C, FAN L
  • 专利权人:   UNIV WUHAN TECHNOLOGY
  • 国际专利分类:   A61L027/02, A61L027/16, A61L027/18, A61L027/54
  • 专利详细信息:   CN114796601-A 29 Jul 2022 A61L-027/16 202293 Chinese
  • 申请详细信息:   CN114796601-A CN10551990 20 May 2022
  • 优先权号:   CN10551990

▎ 摘  要

NOVELTY - Preparing composite piezoelectric film comprises adding graphene oxide-polydopamine (GO-PDA) dispersion into piezoelectric polymer solution under stirring uniformly in a mass ratio of (2-12.5) mg: (1-3) g to obtain a mixed solution. The GO-PDA dispersion is obtained by adding GO-PDA particles to the organic solvent I. The mixed solution is formed into a film by a solvent casting method, and after drying, annealing treatment and corona polarization treatment are performed in sequence to obtain the composite piezoelectric film. USE - Method for preparing a composite piezoelectric film for inducing bone regeneration from bone defects in the context of chronic inflammation (claimed). ADVANTAGE - The composite piezoelectric film adopts the solvent casting method, which is convenient for large-scale production. The prepared film is uniform and tough, and has excellent mechanical properties, which can meet the mechanical strength after implantation in the body, restore the electrical microenvironment of the cells, and thus make the inter-medullary membrane easier to obtain Mesenchymal stem cells (MSCs) differentiate into osteoblasts.