▎ 摘　　要

NOVELTY - Preparing multifunctional antibacterial hydrogel dressing involves modifying quaternary ammonium salt (QAS) by dihydroxy and oxadiazolyl with excellent antibacterial property, by isophorone diisocyanate (IPDI) coupling water-soluble natural antibacterial active glycan carboxymethyl chitosan (CMCS), constructing quaternized carboxymethyl chitosan (QCS), functionalizing the two-dimensional photo-thermal material (GO) with 3-amino phenylboronic acid (PBA), performing reduction reaction to prepare functional reduction graphene oxide (rGB), pre-polymerizing the dopamine (DA), performing secondary polymerization in the initiator ammonium persulfate (APS), dissolving a certain proportion of quaternary ammonium salt antibacterial active polysaccharide (QCS), acrylamide (AM) into the pre-polymerized dopamine (DA) solvent. USE - Method for preparing multifunctional antibacterial hydrogel dressing used to wound healing process wound healing dressing, antibacterial dressing, medical adhesive, medical surgical suture line and artificial tissue skin (claimed). ADVANTAGE - The method is reliable and safety compatibility, has good economical efficiency, solves the problem that the current wound dressing mechanical property is bad, adhesion performance is deleted, antibiotic drug abuse problem. DETAILED DESCRIPTION - Preparing multifunctional antibacterial hydrogel dressing involves modifying quaternary ammonium salt (QAS) by dihydroxy and oxadiazolyl with excellent antibacterial property, by isophorone diisocyanate (IPDI) coupling water-soluble natural antibacterial active glycan carboxymethyl chitosan (CMCS), constructing quaternized carboxymethyl chitosan (QCS), functionalizing the two-dimensional photo-thermal material (GO) with 3-amino phenylboronic acid (PBA), performing reduction reaction to prepare functional reduction graphene oxide (rGB), pre-polymerizing the dopamine (DA), performing secondary polymerization in the initiator ammonium persulfate (APS), dissolving a certain proportion of quaternary ammonium salt antibacterial active polysaccharide (QCS), acrylamide (AM) into the pre-polymerized dopamine (DA) solvent and adding 3-amino phenylboronic acid functionalized reducing graphene oxide (rGB) according to a certain proportion, after mixing uniformly and subjecting to in-situ initiating polymerization to obtain product.