▎ 摘　　要

NOVELTY - Use of nano-metal-organic framework material in electrochemiluminescence sensor for (ECL) detection of micro-RNA, is claimed. The nano-metal-organic framework material comprises nano-layer formed from tetra(carboxyphenyl)porphyrin and zinc through coordination of carboxy groups on benzene ring, and space between the nano-layers formed by coordination between the zinc and carboxy group of 4,4'-biphenyldicarboxylic acid and tetra(carboxyphenyl)porphyrin, at the same time, zinc also coordinately binds to nitrogen in the porphyrin ring of tetra(carboxyphenyl)porphyrin. USE - Use of nano-metal-organic framework material in electrochemiluminescence sensor for (ECL) detection of micro-RNA i.e. micro-RNA-24 (all claimed). ADVANTAGE - The nano-metal-organic framework material is two-dimensional metal-organic framework zinc porphyrin complex, and provides ECL sensor with high detection sensitivity and accuracy, and specificity for micro-RNA24 through nucleic acid signal amplification. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following: (1) ECL sensor for micro-RNA detection, which comprises electrodes containing zinc complex-doped graphene quantum dots, DNA strand (HP1) that can specifically bind to target micro-RNA, DNA strand (HP2) capable of replacing the target micro-RNA complexed with the DNA strand (HP1), DNA strand (HP3) and DNA strand (HP4) that can be linked to DNA strand (HP2) and circulate alternately; and (2) method for detecting micro-RNA, which involves using the ECL sensor.