• 专利标题:   Electrode for use in electrode carrier for detecting, receiving and/or inducing physiological electrical signals, comprises electrode base material, and anchoring material for attaching carbon material to base material.
  • 专利号:   WO2022258210-A1
  • 发明人:  
  • 专利权人:   INBRAIN NEUROELECTRONICS SL
  • 国际专利分类:   A61B005/00, A61B005/053, A61N001/05, A61N001/375
  • 专利详细信息:   WO2022258210-A1 15 Dec 2022 A61N-001/05 202308 Pages: 24 English
  • 申请详细信息:   WO2022258210-A1 WOEP082725 24 Nov 2021
  • 优先权号:   EP382525

▎ 摘  要

NOVELTY - The electrode (10) has an electrode base material, a carbon material, and an anchoring layer i.e. monolayer, located between the electrode base and the carbon materials. The anchoring structure has a chain of 10 consecutive covalently bonded atoms. The carbon material is a graphene material or a graphene oxide or a reduced graphene oxide. A distal end or a proximal end of the structure is covalent bound to the carbon material by a distal substructure and a proximal substructure. A proximal hetero atom is preferably a sulfur atom, a gold atom, or a subunit. The electrode base material comprises gold, iridium, platinum, titanium, silver, and/or palladium. USE - Electrode for use in an electrode carrier (claimed) for detecting, receiving and/or inducing physiological electrical signals, and for neurostimulation e.g. cortical and deep brain stimulation, for diagnosis and therapy of neurodegenerative diseases e.g. inter alia drug-resistant parkinson's disease, epilepsy, and chronic pain, for a human patient. ADVANTAGE - The anchoring material is highly inert and mechanically robust, thus avoiding degradation problems. The electrode has improved adhesion of films based on graphene oxide to metallic electrode base materials, and is highly favorable for safe electrical interfacing in aqueous environments, and provides long-term neurostimulation for cortical and/or deep brain stimulation. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for: a method for preparing an electrode; an electrode carrier for detecting; and a use of an anchoring compound having a chain ofeight consecutive covalently bonded atoms for attaching a carbon material to an electrode base material. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of an electrode carrier comprising a set of electrodes. 10Electrode 11Electrode carrier