▎ 摘　　要

NOVELTY - The device (100) has an upper substrate (20) and a lower substrate (10). A graphene thin film (11) is arranged on a lower end of the upper substrate and the upper end of the lower substrate, respectively. The reaction spaces detect biological molecules in a sample that are positioned in a space between the graphene thin film of the upper and lower substrates. A light source irradiates light to the graphene thin film. The light is exposed from the light source. A sample is located in the reaction space that is caused through plasmonic photothermal light-to-heat conversion inside the graphene thin film. A temperature sensor monitors the temperature of the biological molecule. USE - Biological molecule detection device. ADVANTAGE - The light absorption is improved through surface plasmon resonance. The manufacturing cost is reduced in the process using gold foil. DETAILED DESCRIPTION - A controller is coupled to the light source and the temperature sensor. The controller controls the acquisition of data from the temperature sensor and the operation of the light source. The nanometer-sized graphene quantum dot particles improve the light absorption through surface plasmon resonance. The microfluidic chip includes a microfluidic channel. A primer pair has a base sequence complementary to a biological target molecule in the sample, four dNTP molecules, and a polymerase that are placed in the reaction space. The graphene quantum dots are mixed thin film, biological molecular detection device manufactured by a roll-to-roll process. The biological molecule, nucleic acid, and protein are selected from the group consisting of peptides and polypeptides. An imprinting unit imprints reaction spaces for detecting biological molecules in a sample on the graphene-coated substrate. A laminating unit laminates an upper portion of the reaction space with a graphene-coated substrate. DESCRIPTION OF DRAWING(S) - The drawing shows a cross-sectional view of a biological molecule detection device manufactured by a roll-to-roll process. Lower substrate (10) Graphene thin film (11) Upper substrate (20) Biological molecule detection device (100)