▎ 摘　　要

NOVELTY - Composition of poly (e-caprolactone) and graphene oxide for use in killing bacteria that cause infections in patients implanted with medical devices comprises: (a) a solvent comprising tetrahydrofuran; (b) 5-7.5 wt.%, preferably 5 wt.% graphene oxide; (c) 5-7.5% preferably 7.5 wt.% poly (e-caprolactone); and (d) a coagulation non-solvent comprising ethanol. USE - The composition is useful for killing bacteria that cause infections in patients implanted with medical devices, where the bacteria Staphylococcus epidermidis and Escherichia coli (all claimed). Test details are described but no results given. ADVANTAGE - The composition: has biocompatibility; and utilizes poly(e-caprolactone)/graphene oxide scaffolds and medical devices and 3D printed fibrous scaffolds that have reduced risk of implant-associated infections. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for: (1) fibrous scaffold of poly (e-caprolactone) and graphene oxide comprises the composition; (2) medical device comprising the composition or scaffold, where the medical device comprising surgical suture, 3 dimensional (D) scaffolds for tissue engineered implants as well as other non-limiting examples of implantable medical devices such as a stent, vascular implant, dental implant, or bone implant; and (3) constructing the fibrous scaffold of poly(e-caprolactone) and graphene oxide by additive manufacturing and wet-spinning of comprising dispersing graphene oxide in tetrahydrofuran, 5-7.5 wt.% preferably 5 wt.% solvent, dissolving 7.5-15%, preferably 7.5 wt.% poly (e-caprolactone) in the previous mixture, loading the previous mixture into a syringe or a 3D printer head, extruding the tetrahydrofuran/poly(e-caprolactone)/graphene oxide mixture into a coagulation bath consisting of ethanol rinsing poly(e-caprolactone)/graphene oxide scaffolds with ethanol and drying the scaffolds.