▎ 摘　　要

NOVELTY - Preparing chloroquine phosphate molecularly imprinted electrochemical sensor involves adding 50-54 wt.% nano gallium nitride, 18-22 wt.% graphene oxide, 10-14 wt.% 1-butanesulfonic acid-2-methylimidazole chloride, 6-10 wt.% liquid paraffin and 6-10 wt.% heptane in agate mortar. The sum of mass percentages of each component is 100 wt.%. The mixture is uniformly grounded to obtain mixed carbon paste. The carbon paste is placed into glass tube with inner diameter of psi 4.5 mm connected with wire, compacted, dried, polished with polishing powder, and washed with deionized water to obtain gallium nitride paste electrode sensor. The 66-70 wt.% ethanol, 24-28 wt.% gamma -aminopropyltrimethoxysilane and 4-8 wt.% carbon quantum dots are added, and stirred to dissolve. The polished gallium nitride paste electrode is placed, and soaked at room temperature for 4 hours. The temperature is raised to 50 plus minus 2 degrees C, and reacted at constant temperature for 2 hours. USE - Method for preparing chloroquine phosphate molecularly imprinted electrochemical sensor. ADVANTAGE - The method enables to prepare chloroquine phosphate molecularly imprinted electrochemical sensor that has high sensitivity and selectivity, good specificity and rapid detection. DETAILED DESCRIPTION - Preparing chloroquine phosphate molecularly imprinted electrochemical sensor involves adding 50-54 wt.% nano gallium nitride, 18-22 wt.% graphene oxide, 10-14 wt.% 1-butanesulfonic acid-2-methylimidazole chloride, 6-10 wt.% liquid paraffin and 6-10 wt.% heptane in agate mortar. The sum of mass percentages of each component is 100 wt.%. The mixture is uniformly grounded to obtain mixed carbon paste. The carbon paste is placed into glass tube with inner diameter of psi 4.5 mm connected with wire, compacted, dried, polished with polishing powder, and washed with deionized water to obtain gallium nitride paste electrode sensor. The 66-70 wt.% ethanol, 24-28 wt.% gamma -aminopropyltrimethoxysilane and 4-8 wt.% carbon quantum dots are added, and stirred to dissolve. The polished gallium nitride paste electrode is placed, and soaked at room temperature for 4 hours. The temperature is raised to 50 plus minus 2 degrees C, and reacted at constant temperature for 2 hours. The electrode is taken out, washed with absolute ethanol, and dried to obtain carbon quantum dot modified gallium nitride paste electrode. The 62-68 wt.% ethanol, 6-10 wt.% itaconic acid, 10-14 wt.% 4-aminopyridine, 6-10 wt.% chloroquine phosphate, 4-8 wt.% 1,4-butanediol dimethacrylate and 1.0-3.0 wt.% azobisisoheptonitrile are added, stirred to dissolve, deoxidized with nitrogen for 15 minutes at anaerobic atmosphere of 60 plus minus 2 degrees C, and stirred for 4-6 hours. The obtained product is soaked in mixed solution of alcohol and hydrochloric acid with volume ratio of 6:1 for 8 hours, washed multiple times to remove template molecules, and dried to obtain chloroquine phosphate molecularly imprinted polymer. The 94-96 wt.% acetone, 2-4 wt.% polyamide and 1.5-3.0 wt.% chloroquine phosphate molecularly imprinted polymer are added. The chloroquine phosphate molecularly imprinted polymer modification solution is prepared. The 40-50 microliter solution is added dropwise to carbon quantum dot modified gallium nitride paste electrode, and placed under infrared lamp. The dry solvent is evaporated to obtain chloroquine phosphate molecularly imprinted electrochemical sensor.