• 专利标题:   Paramagnetic chiral graphene quantum dot useful for monitoring interaction between chiral molecules, comprises e.g. chiral graphene quantum dots and chelating agent form covalent bond through mutual functional group reaction.
  • 专利号:   CN113234442-A, CN113234442-B
  • 发明人:   DONG H, LI Y, YANG S, TAO Q, DING G, XIE X
  • 专利权人:   SHANGHAI INST MICROSYSTEM INFORMATION
  • 国际专利分类:   B82Y020/00, B82Y040/00, C01B032/184, C01B032/194, C07D257/02, C07D265/32, C07F005/00, C09K011/02, C09K011/65, G01N021/64, G01N024/08, H01F001/00, H01F041/00
  • 专利详细信息:   CN113234442-A 10 Aug 2021 C09K-011/65 202176 Pages: 14 Chinese
  • 申请详细信息:   CN113234442-A CN10509612 11 May 2021
  • 优先权号:   CN10509612

▎ 摘  要

NOVELTY - Paramagnetic chiral graphene quantum dot comprises chiral graphene quantum dots, chelating agents and paramagnetic metal ions. The chiral graphene quantum dots and the chelating agent form a covalent bond through the reaction of functional groups with each other. The chelating agent and a paramagnetic metal ion are bonded through coordination bond. USE - The paramagnetic chiral graphene quantum dot is useful for monitoring interaction between chiral molecules (claimed). ADVANTAGE - The paramagnetic chiral graphene quantum dot has strong stability; combines fluorescence properties, chirality, and paramagnetism on the same material; converts chiral interaction process into magnetic signal read by the nuclear magnetic resonance device, and converts the chiral interaction process into optical signal to read; and utilizes both magnetic and optical signals for dual-mode signal reading. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for: (1) preparing paramagnetic chiral graphene quantum dots, comprising condensing chiral amino acids by hydrothermal reaction to obtain chiral graphene quantum dots, then reacting with a chelating agent, and adding paramagnetic ions to form paramagnetic chiral graphene quantum dot material; and (2) use of paramagnetic chiral graphene quantum dot for monitoring the interaction between chiral molecules, comprising dispersing the paramagnetic chiral graphene quantum dots in an aqueous, and then sensing the interaction between chiral molecules and output magnetic signals and/or optical signals.