▎ 摘 要
NOVELTY - Preparation of antibacterial medical coating nonwoven fabric includes preparation of modified whiskers by adding nano-zinc oxide whisker and nano-titanium dioxide whisker into ethanol solution to mix uniformly, adding silane coupling agent, adjusting the pH at 5, continuously stirring and reacting for 40 minutes to obtain modified whisker, adding N,N-dimethylformamide into a spinning solution, stirring and mixing uniformly, increasing the rotating speed to 1200 revolutions/minute (rpm), adding modified whisker, conductding electrostatic spinning, obtaining modified yarn, making the modified yarn into nonwoven fabric A, soaking the nonwoven fabric A in ethanol for 20 minutes, at 24degrees Celsius, adding sodium hydroxide solution, continuously stirring and reacting for 15 minutes, taking out, drying to obtain nonwoven fabric B, putting sodium hydroxide in chloroacetic acid solution, stirring and dissolving, and sequentially adding acrylic acid and benzophenone. USE - The method is for preparation of antibacterial medical coating nonwoven fabric. ADVANTAGE - The method enables to prepare antibacterial medical coating nonwoven fabric that has excellent antibacterial performance, strongest hemostatic effect, high tensile breaking strength, water solubility, and very wide application prospect. DETAILED DESCRIPTION - Preparation of antibacterial medical coating nonwoven fabric comprises preparation of modified whiskers by adding nano-zinc oxide whisker and nano-titanium dioxide whisker into ethanol solution to mix uniformly, adding silane coupling agent, adjusting the pH at 5, continuously stirring and reacting for 40 minutes to obtain modified whisker, adding N,N-dimethylformamide into a spinning solution, stirring and mixing uniformly, increasing the rotating speed to 1200 rpm, adding modified whisker, conductding electrostatic spinning, obtaining modified yarn, making the modified yarn into nonwoven fabric A, soaking the nonwoven fabric A in ethanol for 20 minutes, at 24degrees Celsius, adding sodium hydroxide solution, continuously stirring and reacting for 15 minutes, taking out, drying to obtain nonwoven fabric B, putting sodium hydroxide in chloroacetic acid solution, stirring and dissolving, sequentially adding acrylic acid and benzophenone, stirring uniformly, adjusting the pH at 7, putting in nonwoven fabric B, soaking for 1.5 hours, taking out, washing with ethanol, and putting under UV lamp for 4.5 hours to obtain the nonwoven fabric substrate; preparing coating A by preparing modified graphene oxide by placing graphene oxide in ethanol solution, ultrasonically dispersing for 30 minutes, sequentially adding zinc acetate and sodium hydroxide solution, stirring and reacting for 1.5 hours, raising the temperature to 155degrees Celsius, adding silver nitrate, continuously stirring, reacting for 22 hours at constant temperature, washing and drying by deionized water, placing in urea solution at 100degrees Celsius, stirring and reacting for 30 minutes, washing by deionized water and drying to obtain the modified graphene oxide, at room temperature, adding chitosan into acetic acid solution, stirring and dissolving, raising the temperature to 55degrees Celsius, adding lauric acid anhydride and ethanol solution, continuously stirring, reacting for 13 hours at constant temperature, sequentially adding glacial acetic acid coating base material and modified graphene oxide, stirring to obtain coating A, coating the coating A on the lower surface of the nonwoven fabric substrate, reacting for 9 hours, and UV lamp curing for 4.5 hours at 135degrees Celsius; and preparing coating B by putting ethyl cellulose in dichloromethane, stirring and dissolving, adding plant extract solution and emulsifier, stirring for 35 minutes at 1200 rpm, adding melted gelatin and sodium dodecyl sulfate, low speed stirring at 300 rpm to obtain antibacterial microcapsule, at 55degrees Celsius, mixing chitosan, porous starch, and deionized water uniformly, sequentially adding anhydrous sodium carbonate and sodium trimetaphosphate, stirring and reacting for 1.5 hours, adjusting pH to 6, sequentially adding adhesive, antibacterial microcapsule, and agar, stirring to obtain coating B, coating the coating B on the upper surface of the nonwoven fabric substrate, and UV lamp curing for 4.5 hours at 135degrees Celsius to obtain antibacterial nonwoven fabric comprising 95 pts. wt. nonwoven fabric substrate, 20 pts. wt. coating A, and 20 pts. wt. coating B. The nonwoven fabric substrate comprises 25 pts. wt. modified crystal whisker, 80 pts. wt. spinning solution, 10 pts. wt. chloroacetic acid, 10 pts. wt. acrylic acid, and 10 pts. wt. benzophenone. The modified whisker comprises 25 pts. wt. nano-zinc oxide crystal whisker, 25 pts. wt. nano-titanium dioxide crystal whisker, and 13 pts. wt. silane coupling agent. The coating A comprises 25 pts. wt. modified graphene oxide, 13 pts. wt. lauric acid anhydride, 15 pts. wt. glacial acetic acid, and 45 pts. wt. coating base material. The modified graphene oxide comprises 55 pts. wt. graphene oxide, 9 pts. wt. zinc acetate, 15 pts. wt. sodium hydroxide, and 20 pts. wt. silver nitrate. The coating B comprises 25 pts. wt. antibacterial microcapsule, 35 pts. wt. porous starch, 15 pts. wt. anhydrous sodium carbonate, 13 pts. wt. sodium trimetaphosphate, and 50 pts. wt. coating base material. The antibacterial microcapsule comprises 30 pts. wt. ethyl cellulose, 25 pts. wt. plant extract solution, 15 pts. wt. emulsifier, 40 pts. wt. gelatin, and 17 pts. wt. sodium dodecyl sulfate. The coating base material comprises 50 pts. wt. chitosan, 20 pts. wt. adhesive, and 12 pts. wt. agar.