• 专利标题:   Nanographene-sensor or diagnostic kit for detecting nucleic acid in a nuclear nucleus, for diagnosing neurodegenerative disease, comprises graphene containing a nuclear transition signal, and a probe containing a fluorescent substance.
  • 专利号:   KR2018065746-A
  • 发明人:   HWANG D W, LEE D S
  • 专利权人:   UNIV SEOUL NAT R DB FOUND
  • 国际专利分类:   C12Q001/68, C01B031/04, C07K014/00, C07K007/06, C07K007/08
  • 专利详细信息:   KR2018065746-A 18 Jun 2018 C12Q-001/68 201852 Pages: 26
  • 申请详细信息:   KR2018065746-A KR166979 08 Dec 2016
  • 优先权号:   KR166979

▎ 摘  要

NOVELTY - Nanographene-sensor or diagnostic kit comprises a graphene containing a nuclear transition signal, and a probe containing a fluorescent substance. USE - Nanographene-sensor or diagnostic kit for detecting a nucleic acid in a nuclear nucleus, for diagnosing the neurodegenerative disease by using probe, Where neurodegenerative disease is selected from a group consist of Parkinson's disease, Alzheimer's disease, Huntington's disease, amyotrophic lateral sclerosis and multiple sclerosis, for diagnosing the nerve development failure (all claimed). ADVANTAGE - The nanographene-sensor or diagnostic kit provides high reliability and resolution results, carries out detection in simple, rapid and accurate manner in living tissue or cell, easily observes inhibitory effect of nucleic acid in the nucleus in treating small interfering RNA, and helps to determine a rapid treatment policy. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for detecting nucleic acid in a nuclear nucleus, which involves mixing a sample with the nanographene sensor or the diagnostic kit.