▎ 摘　　要

NOVELTY - An intravascular catheter comprises (a) a catheter tube comprising a lumen and a set of side holes, where the side holes are distributed along the length of the catheter tube in a spiraling corkscrew pattern; and (b) a biocompatible bioscaffold comprising a set of macropores and micropores, where the biocompatible bioscaffold is contained within the catheter lumen. USE - An intravascular catheter for implanting therapeutic cells in a subject, treating a subject for type 1 diabetes and for kit (all claimed). ADVANTAGE - Upon placement of the catheter in a vein, the side holes allow blood to flow though the catheter supplying oxygen and nutrients to any loaded cellular cargo and also providing for the removal of waste products. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for: (1) implanting therapeutic cells in a subject which involves placing the intravascular catheter within a major vein of the subject; (2) treating a subject for type 1 diabetes which involves placing the intravascular catheter within a major vein of the subject; (3) kit comprising (a) intravascular catheter; and (b) a packaging comprising a compartment for holding the intravascular catheter; (4) producing the intravascular catheter which involves (a) combining polydimethylsiloxane (PDMS) with a porogen to produce a PDMS-porogen mixture; (b) placing the PDMS-porogen mixture inside the catheter lumen; (c) curing the PDMS-porogen mixture inside the catheter lumen; (d) adding a set of side holes to the catheter tube, where the side holes are distributed along the length of the catheter tube in a spiraling corkscrew pattern; and (e) removing the porogen from the PDMS-porogen mixture, where a PDMS bioscaffold comprising a set of macropores and micropores is produced inside the catheter lumen; and (5) producing an intravascular catheter which involves forming a catheter tube comprising a set of side holes using three-dimensional (3D) printing, where the side holes are distributed along the length of the catheter tube in a spiraling corkscrew pattern; and forming a biocompatible bioscaffold using the 3D printing, where the biocompatible bioscaffold is contained inside the catheter lumen. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of the hybrid PDMS bioscaffold-intravascular catheter in the bloodstream.