• 专利标题:   Preparing composite medicine-loaded gel comprises mixing e.g. pyrrole and dopamine hydrochloride to water, reacting, adding composite material in e.g. medicine molecule and graphene oxide solution and calcium chloride solution and stirring.
  • 专利号:   CN113181108-A, CN113181108-B
  • 发明人:   DU H, YU X, LI L, LIU H, LIU Y
  • 专利权人:   WUHAN INST TECHNOLOGY
  • 国际专利分类:   A61K031/519, A61K031/704, A61K047/04, A61K047/34, A61K047/61, A61K009/06
  • 专利详细信息:   CN113181108-A 30 Jul 2021 A61K-009/06 202174 Pages: 7 Chinese
  • 申请详细信息:   CN113181108-A CN10331349 25 Mar 2021
  • 优先权号:   CN10331349

▎ 摘  要

NOVELTY - Preparing composite medicine-loaded gel comprises (a) adding pyrrole and dopamine hydrochloride into water, mixing uniformly, adding ammonium persulfate, stirring, reacting, centrifuging, washing to obtain polypyrrole-polydopamine nano composite material, (b) placing the nano composite material in 1mol/l hydrochloric acid solution containing medicine molecule and graphene oxide aqueous solution, centrifuging, absorbing to obtain graphene oxide-polypyrrole-poly-dopamine nano composite medicine loading material and (c) mixing the nano composite medicine -loading material with the aqueous soluble polymer solution, adding calcium chloride solution, stirring and allowing to stand to obtain the composite medicine-loaded gel. USE - The method is useful for preparing composite medicine-loaded gel. ADVANTAGE - The method promotes the formation of composite medicine -loaded gel; slowdowns the sudden release phenomenon in the initial stage of medicine release and ensures that the composite medicine -loaded gel has multiple stimulation responsiveness. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for composite medicine -loaded gel.