▎ 摘　　要

NOVELTY - Preparing controllable phospholipid micelle comprises (i) removing solvent of phospholipid chloroform solution, drying, removing chloroform solvent, adding deionized water, using micro-extruder to extrude to obtain small phospholipid vesicle solution; (ii) pressing transparent adhesive tape on the surface of the large graphene flat layer, tearing quickly in parallel, obtaining the flat graphene thin layer on the transparent adhesive tape; (iii) dropping small phospholipid vesicle solution and salt solution on graphene thin electrode substrate, incubating, and washing to obtain thin electrode; and (iv) setting electrochemical potential, connecting the incubated thin-layer electrode and platinum wire electrode to the electrode of the electrochemical workstation, reacting obtaining phospholipid micelles of different depths and widths on thin-layer electrodes, and maintaining phospholipid micelles maintained stable micellar morphology USE - The method is useful for preparing controllable phospholipid micelle. ADVANTAGE - The method has unique design, simple operation, fast formation speed, short preparation period and good controllability. DETAILED DESCRIPTION - Preparing controllable phospholipid micelle comprises (i) removing solvent of phospholipid chloroform solution, placing into a vacuum drying box, drying, removing chloroform solvent, adding deionized water, ultrasonically treating, using micro-extruder to extrude to obtain small phospholipid vesicle solution with size of 100-200 nm; (ii) pressing the transparent adhesive tape on the surface of the large graphene flat layer, tearing quickly in parallel, obtaining the flat graphene thin layer on the transparent adhesive tape i.e. graphene thin-layer electrode substrate; (iii) dropping small phospholipid vesicle solution and salt solution on graphene thin electrode substrate, incubating at 50-70degrees Celsius, and washing the sample to obtain thin electrode; and (iv) setting electrochemical potential 2V to +2V at 50-70degrees Celsius, connecting the incubated thin-layer electrode and platinum wire electrode to the electrode of the electrochemical workstation, reacting for 2-10 minutes, obtaining phospholipid micelles of different depths and widths on thin-layer electrodes, and maintaining phospholipid micelles maintained stable micellar morphology at less than 40degrees Celsius.