• 专利标题:   Thickened antibacterial polyaspartic acid solution used in daily chemicals and cosmetics e.g. shampoo, comprises sodium polyaspartate, alkyltrimethylammonium chloride, dodecyldimethylbenzylammonium chloride, ethylhexylglycerin, modifier, and pure water.
  • 专利号:   CN113549326-A
  • 发明人:   ZHUANG W, CHEN L, WU Y
  • 专利权人:   SUZHOU MEIRUIZI BIOTECHNOLOGY CO LTD
  • 国际专利分类:   A61K008/19, A61K008/20, A61K008/33, A61K008/41, A61K008/73, A61K008/88, A61Q017/00, A61Q005/02, A61Q005/12, C08K013/02, C08K003/04, C08K003/22, C08K005/06, C08K005/19, C08L001/02, C08L005/08, C08L079/08
  • 专利详细信息:   CN113549326-A 26 Oct 2021 C08L-079/08 202214 Chinese
  • 申请详细信息:   CN113549326-A CN10964288 22 Aug 2021
  • 优先权号:   CN10964288

▎ 摘  要

NOVELTY - A thickened antibacterial polyaspartic acid solution comprises 19.50-21.50 wt.% sodium polyaspartate, 2.60-6.40 wt.% alkyltrimethylammonium chloride, 0.80-1.40 wt.% dodecyldimethylbenzylammonium chloride, 0.05-0.08 wt.% ethylhexylglycerin, 2.50-3.10 wt.% modifier, and remainder of pure water. USE - Thickened antibacterial polyaspartic acid solution is used in daily chemicals and cosmetics e.g. shampoo (all claimed). ADVANTAGE - The thickened antibacterial polyaspartic acid solution can effectively improve thickening, antibacterial, moisturizing, repairing and deodorizing property of shampoo, effectively strengthen heavy metal ion absorption and removal effect of shampoo, effectively reduce residual amount of heavy metal ions on scalp and skin, and reduce heavy metal ion damage to scalp and skin of user. Combine bulk cations with polyaspartic acid anions to form water-in-oil reverse micelles, which can achieve the purpose of solubilization by forming reverse micelles, and effectively prevent demulsification and viscosity reduction problems of the polyaspartic acid solution in water-oil mixed system and promote dissolution of polyaspartic acid. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for preparation of the thickened antibacterial polyaspartic acid solution, which involves (i) weighing sodium polyaspartate, alkyltrimethylammonium chloride, dodecyldimethylbenzylammonium chloride, ethylhexylglycerin, pure water, and modifier comprising nanocellulose, concentrated chitosan, glutaraldehyde, graphene, ferrous chloride, ammonium bicarbonate and deionized water, (ii) blending the nanocellulose, graphene, ferrous chloride, ammonium bicarbonate and deionized water, passing nitrogen and air for 10-20 minutes and ultrasonically-treating to obtain a mixture (a), (iii) adding the chitosan and glutaraldehyde to the mixture (a), ultrasonically-treating for 30-40 minutes by hydrothermal method and electrospinning to obtain modifier, (iv) mixing sodium polyaspartate with 1/2 portion of total amount of pure water to obtain a sodium polyaspartate solution, (v) adding alkyltrimethylammonium chloride to the sodium polyaspartate solution and heating and stirring at 40-70degrees Celsius for 1-3 hours until it is completely dissolved to obtain a mixture (b), (vi) adding the modifier to the mixture (b) and ultrasonically-treating for 30-40 minutes to obtain a mixture (c), (vii) adding dodecyldimethylbenzylammonium chloride to the mixture (c) and continuously stirring for 1-2 hours to obtain a mixture (d), (viii) adding ethylhexylglycerin and remaining pure water to the mixture (d) and ultrasonically-treating for 30-40 minutes to obtain a mixture (e), and (ix) cooling the mixture (e) to room temperature and filtering using a microfiltration membrane.