▎ 摘　　要

NOVELTY - A nanoparticle comprises a core comprising a magnetic metal; a graphene coating surrounding the core; and a targeting moiety conjugated to the graphene coating. USE - The nanoparticles and pharmaceutical composition are used for treating a bacterial infection, a viral infection, a parasite infection, an autoimmune disease or a cell hyperproliferative disease, where the cell hyperproliferative disease is a cancer (all claimed). ADVANTAGE - New particles with require a lower dosage than conventional therapies and which results to fewer and more mild side effects are provided. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are: (1) a method for making a nanoparticle by (a) reducing a metal salt to form a magnetic metal nanoparticle; (b) depositing a graphene coating on the particle by microwave arc discharge; and (c) conjugating the nanoparticle to a targeting moiety; (2) a method of treating a subject by (a) administering nanoparticles comprising a magnetic metal core; a graphene coating and a targeting moiety to a subject; and (b) applying an alternating current field to the subject, where the amount of nanoparticles administered to the subject and the alternating current field applied to the subject are together effective to produce localized hyperthermia in the subject; and (3) a method of treating.