• 专利标题:   Electrochemical biosensor, useful in e.g. salivary cortisol measurement, comprises an electrode substrate configured for electrical measurements of a functionalized area of a surface of the electrode substrate.
  • 专利号:   WO2021188047-A1
  • 发明人:   XU G, TONG Y W, LI C, CHAI L L C
  • 专利权人:   UNIV SINGAPORE NAT
  • 国际专利分类:   G01N027/30, G01N033/74
  • 专利详细信息:   WO2021188047-A1 23 Sep 2021 G01N-027/30 202184 Pages: 23 English
  • 申请详细信息:   WO2021188047-A1 WOSG050134 16 Mar 2021
  • 优先权号:   SG10002405

▎ 摘  要

NOVELTY - The electrochemical biosensor (600) has an electrode substrate (602) configured for electrical measurements of a functionalized area (604) of a surface of the electrode substrate. The area is formed in a mixture (608) of molecular imprinting polymer (MIP), particles and one or more immobilizer materials. The MIP particles have imprints of a molecule sensed by the biosensor. The electrode substrate comprises a screen-printed carbon electrode and the mixture is provided as a thin film. The immobilizer material comprises chitosan, carbon nanodots, graphene, graphene oxide, or reduced graphene oxide. USE - Electrochemical biosensor e.g. salivary cortisol biosensor for use in cortisol detection and stress screening. Can also be used for monitoring customer wellness. ADVANTAGE - The electrochemical biosensor is highly selective, simple, fast and easy-to-operate, and facilitates the real-time monitoring of consumer wellness. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method of fabricating an electrochemical biosensor. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of an electrochemical biosensor. Electrochemical biosensor (600) Electrode substrate (602) Functionalized area (604) Surface (606) Mixture (608)