• 专利标题:   Producing nanoparticle useful for detecting or quantifying target substance i.e. virus, protein, peptide, DNA or RNA, by producing fluorescent quantum dot, and forming hollow shell portion made of magnetic material surrounding core portion made of quantum dots.
  • 专利号:   WO2021261334-A1, JP2022531842-X
  • 发明人:   PARK E Y, GANGANBOINA A B
  • 专利权人:   UNIV SHIZUOKA NAT CORP
  • 国际专利分类:   G01N033/543, G01N027/02, G01N033/533
  • 专利详细信息:   WO2021261334-A1 30 Dec 2021 202207 Pages: 56 Japanese
  • 申请详细信息:   WO2021261334-A1 WOJP022732 15 Jun 2021
  • 优先权号:   JP107951

▎ 摘  要

NOVELTY - Method (M1) for producing nanoparticle involves (a) producing fluorescent quantum dot, and (b) forming a hollow shell portion made of a magnetic material surrounding the core portion made of the quantum dots. The nanoparticle comprises a core portion made of fluorescent quantum dot, and a hollow shell portion made of a magnetic material surrounding the core portion. The nanoparticle for detecting or quantifying a target substance whose minimum inner diameter of the shell portion is larger than the maximum outer diameter of the core portion. USE - The method (M1) is useful for producing nanoparticle. The nanoparticle is useful in kit for detecting or quantifying target substance. The target substance is a virus, protein, peptide, DNA, or RNA (all claimed). ADVANTAGE - The method (M1) produces nanoparticle which detects target substance with high sensitivity in a rapid and simple manner. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following: (1) a method (M2) for detecting or quantifying a target substance involves using the nanoparticles produced by the above-mentioned production method (M1); and (2) a kit comprising the nanoparticles, and an electrochemical measurement electrode to which a probe specific to the target substance is bound.