• 专利标题:   Preparing primary amine by reductive amination of aldehyde comprises introducing hydrogen into the mixed solution containing aldehyde group compound, catalyst and ammonia water to carry out reductive amination reaction.
  • 专利号:   CN113717054-A
  • 发明人:   MIAO H, FAN X, GAO J, MA J, GAO M, XU J
  • 专利权人:   CAS DALIAN CHEM PHYSICAL INST
  • 国际专利分类:   B01J027/24, C07C209/26, C07C211/27, C07C213/02, C07C217/84, C07D213/38, C07D307/52
  • 专利详细信息:   CN113717054-A 30 Nov 2021 C07C-209/26 202208 Chinese
  • 申请详细信息:   CN113717054-A CN10449693 25 May 2020
  • 优先权号:   CN10449693

▎ 摘  要

NOVELTY - Preparing primary amine by reductive amination of aldehyde comprises introducing hydrogen into the mixed solution containing aldehyde group compound, catalyst and ammonia water to carry out reductive amination reaction to obtain primary amine, where the catalyst comprises a carrier and a metal ruthenium loaded on the carrier, the carrier is a layered material containing alkaline sites. USE - The method is useful for preparing primary amine by reductive amination of aldehyde. ADVANTAGE - The method and the basic sites of the carrier act synergistically, and can achieve high selectivity to primary amines in the presence of a relatively small amount of ammonia. The method and the use of the catalyst have broad application prospects.