• 专利标题:   Preparation of shape memory hydrogel involves adding reduced graphene oxide/hyaluronic acid composite powder to polyvinyl alcohol aqueous solution, defoaming, dripping dilute nitric acid, crosslinking, and washing with deionized water.
  • 专利号:   CN111363167-A
  • 发明人:   LU X, WEI L, LI M, LU Y, SONG H, LEI Z, WENG J
  • 专利权人:   UNIV SOUTHWEST JIAOTONG
  • 国际专利分类:   C08J003/075, C08J003/24, C08K003/04, C08K003/32, C08K005/07, C08L029/04
  • 专利详细信息:   CN111363167-A 03 Jul 2020 C08J-003/075 202063 Pages: 10 Chinese
  • 申请详细信息:   CN111363167-A CN10151275 06 Mar 2020
  • 优先权号:   CN10151275

▎ 摘  要

NOVELTY - Preparation of shape memory hydrogel involves preparing 8 %mass polyvinyl alcohol aqueous solution, adding reduced graphene oxide/hyaluronic acid composite powder, ultrasonically stirring for 0.5 hours, leaving still overnight to defoam, dripping dilute nitric acid, adjusting pH to 3.5, leaving still at 30 degrees C for 24 hours, dripping glutaraldehyde for crosslinking, stirring, leaving still at room temperature to form gel, adding aqueous ammonia on top of gel for mineralization, recrystallizing hyaluronic acid, and washing gel repeatedly with deionized water until it is neutral. USE - Preparation of shape memory hydrogel. ADVANTAGE - The method provides hydrogel with uniform structure, excellent thermal stability, tensile strength increased by 3 times, elongation at break increased by 7 times, excellent shape memory performance under heat-induced stimulation conditions of solvent.