• 专利标题:   Graphene transistor-based DNA sensor useful for DNA detection, comprises e.g. an electronic-grade glass, a grid, source electrode, drain electrode and single-stranded DNA.
  • 专利号:   CN108181367-A
  • 发明人:   LI J, LI S, HUANG K, FAN Q, WANG X
  • 专利权人:   UNIV HUBEI
  • 国际专利分类:   C12Q001/68, G01N027/327
  • 专利详细信息:   CN108181367-A 19 Jun 2018 G01N-027/327 201854 Pages: 16 Chinese
  • 申请详细信息:   CN108181367-A CN11429797 26 Dec 2017
  • 优先权号:   CN11429797

▎ 摘  要

NOVELTY - Graphene transistor-based DNA sensor comprises an electronic-grade glass, a grid, source electrode, drain electrode on the electronic-grade glass provided with the graphene channel between the source electrode and the drain electrode, and the gate is fixed on the surface of the single-stranded DNA. USE - The graphene transistor-based DNA sensor is useful for DNA detection (claimed). ADVANTAGE - The DNA sensor operates at a voltage lower than 1 V and has detection sensitivity of 4 pM. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for: (1) preparing graphene transistor-based DNA sensor, comprising (i) preparing a gate, a source and a drain on the surface of the electronic grade glass such that a channel exists between the source and the drain, (ii) laying graphene on the channel between the source and the drain to obtain a graphene transistor, and (iii) fixing single-stranded DNA on the gate surface of the graphene transistor to obtain a graphene transistor-based DNA sensor; and (2) use of graphene transistor-based DNA sensor for DNA detection, comprising immersing the gate of the graphene transistor-based DNA sensor and the graphene channel portion in the electrolyte containing the DNA to be tested. DESCRIPTION OF DRAWING(S) - The drawing shows a flow chart of the graphene transistor-based DNA sensor (Drawing includes non-English language text).