▎ 摘　　要

NOVELTY - Sample processing involves dispersing graphene oxide uniformly in water ultrasonically to obtain graphene oxide dispersion. The zinc acetate dihydrate dissolved in water to obtain liquid A. The liquid A poured into the graphene oxide dispersion liquid, and mixed uniformly to obtain a mixed liquid. The 2-methylimidazole dissolved in water to obtain liquid B, liquid B poured into the above mixed liquid, stirred and reacted for at least 16 hours, centrifuged, and discarded the supernatant. The remainder is washed with methanol multiple times to wash away unreacted materials. The remaining solids are dried to obtain off-white solids, which are fully ground to obtain ZIF-8@GO powder. The polyacrylonitrile powder fully dissolves in N,N-dimethylformamide solution and addes ZIF-8@GO powder to disperse ZIF-8@GO powder uniformly to obtain a film-forming dispersion liquid. USE - Method for sample processing used for the detection of macrolide antibiotics in honey. ADVANTAGE - The method enables to sample process is simple and convenient to operate, and fast and accurate. DETAILED DESCRIPTION - Sample processing involves dispersing graphene oxide uniformly in water ultrasonically to obtain graphene oxide dispersion. The zinc acetate dihydrate dissolved in water to obtain liquid A, liquid A poured into the graphene oxide dispersion liquid, and mixed uniformly to obtain a mixed liquid. The 2-methylimidazole dissolved in water to obtain liquid B, liquid B poured into the above mixed liquid, stirred and reacted for at least 16 hours, centrifuged, and discarded the supernatant. The remainder is washed with methanol multiple times to wash away unreacted materials. The remaining solids are dried to obtain off-white solids, which are fully ground to obtain ZIF-8@GO powder. The polyacrylonitrile powder fully dissolves in N,N-dimethylformamide solution and addes ZIF-8@GO powder to disperse ZIF-8@GO powder uniformly to obtain a film-forming dispersion liquid. The film-forming dispersion liquid is absorbed, and slowly immersed the metal piece into the film-forming dispersion liquid for 3-7 seconds, taken out quickly, and cured at 100-150 degrees C for 1-3 minutes at least 15 times to obtain ZIF-8@GO film coating. A honey sample is weighed, pH 9.0-9.5 sodium carbonate-sodium bicarbonate buffer solution is added, and mixed well to obtain a sample liquid. The sample solution is aspirated to carry out the film micro-extraction procedure, immersed the ZIF-8@GO film coating in the sample solution, and extracted the film coating at a vibration frequency of 800-1000 revolution per minutes (rpm) for 45-60 minutes. The film coating is immersed in water and washed for 3-7 seconds at a vibration frequency of 800-1000 rpm, and then taken out. The film coating is immersed in a solution consisting of methanol, acetonitrile and water in a volume ratio of 6:3:1, eluted at a vibration frequency of 800-1000 rpm for 30-45 minutes, and then taken out. The eluate is blown dry to obtain a processed honey sample. An INDEPENDENT CLAIM is included for a method for detecting macrolide antibiotics in honey, which involves using processed honey sample obtained by the sample processing method as a test sample.