• 专利标题:   Preparing sodium alginate-silver-carrying graphene composite film for promoting antibacterial and wound healing property, involves adding oxidized graphene sheet to distilled water, and dispersing ultrasonic powder.
  • 专利号:   CN106867005-A
  • 发明人:   LU Y, YAN X, XUE J, HU K, XU W, PAN X, LI F, SONG Y, WU Y, SU Y, HE T, LIU J
  • 专利权人:   UNIV HEFEI TECHNOLOGY
  • 国际专利分类:   A61L015/18, A61L015/28, A61L015/46, C08J005/18, C08K003/04, C08K003/08, C08K009/10, C08L005/04
  • 专利详细信息:   CN106867005-A 20 Jun 2017 C08J-005/18 201756 Pages: 11 Chinese
  • 申请详细信息:   CN106867005-A CN10104161 24 Feb 2017
  • 优先权号:   CN10104161

▎ 摘  要

NOVELTY - Preparing sodium alginate-silver-carrying graphene composite film involves adding 100-300mg oxidized graphene sheet to 150-300mL distilled water, and dispersing the ultrasonic powder by adding 2g sodium polystyrene sulfate, stirring and dissolving to obtain mixture. The obtained mixture is mixed with 150-400L hydrazine hydrate, heating and the reaction is carried out at 100 degrees C for 24 hours, and filter and lyophilized to obtain reduced type oxidized graphene-polystyrene sodium sulfate complex. USE - Method for preparing sodium alginate-silver-carrying graphene composite film for promoting antibacterial and wound healing property for dressing (all claimed). ADVANTAGE - The method enables to prepare sodium alginate-silver-carrying graphene composite film, which has great clinical application potential, and is processed in simple manner. DETAILED DESCRIPTION - Preparing sodium alginate-silver-carrying graphene composite film involves adding 100-300mg oxidized graphene sheet to 150-300mL distilled water, and dispersing the ultrasonic powder by adding 2g sodium polystyrene sulfate, stirring and dissolving to obtain mixture. The obtained mixture is mixed with 150-400L hydrazine hydrate, heating and the reaction is carried out at 100 degrees C for 24 hours, and filter and lyophilized to obtain reduced type oxidized graphene-polystyrene sodium sulfate complex. The obtained reduced-type oxidized graphene-polystyrene sodium sulfate complex is mixed with 50-100mL water, mixing, and placing it in a single neck flask, and heating at 60 degrees C to obtain composite. The obtained composite is mixed with 5-10mL silver nitrate solution with the concentration of 0.02mol/L and poured into the flask at a rate of 0.5mL/hour and stirred at constant temperature for 10 hours to obtain solution. The obtained solution is centrifuged to obtain supernatant. The obtained supernatant is mixed with silver-containing graphene solution and 5-25mL sodium alginate solution in a concentration of 15-35mg/mL to obtain the desired product.