• 专利标题:   Multifunctional graphene oxide-chitosan composite hemostatic sponge used for preparing hemostatic material for, e.g. rapid hemostasis comprises graphene oxide, polyethylene glycol diacrylate, methacryloyl chitosan, and antibacterial agent.
  • 专利号:   CN111450308-A
  • 发明人:   WANG X, XU C
  • 专利权人:   UNIV BEIJING CHEM TECHNOLOGY
  • 国际专利分类:   A61L015/18, A61L015/20, A61L015/26, A61L015/28, A61L015/42, A61L015/46, A61L024/00, A61L024/02, A61L024/04, A61L024/08, C08B037/08, C08F299/02
  • 专利详细信息:   CN111450308-A 28 Jul 2020 A61L-024/08 202068 Pages: 11 Chinese
  • 申请详细信息:   CN111450308-A CN10519574 09 Jun 2020
  • 优先权号:   CN10519574

▎ 摘  要

NOVELTY - A multifunctional graphene oxide-chitosan composite hemostatic sponge comprises graphene oxide, polyethylene glycol diacrylate, methacryloyl chitosan, and antibacterial agent. USE - The multifunctional graphene oxide-chitosan composite hemostatic sponge is used for preparing hemostatic material (claimed) for various wounds, rapid hemostasis and healing wound. ADVANTAGE - The sponge is convenient to carry, can seal the wound during emergency hemostasis to prevent blood loss and reduce the chance of secondary bleeding when the material is removed, and has unique selective adhesion properties, good biocompatibility, and simple preparation. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for preparation of the sponge comprising mixing methacrylylated chitosan solution, graphene oxide solution and polyethylene glycol diacrylate at room temperature to obtain brown-black mixed liquid, adding initiator solution, adding to reactor mold, crosslinking, washing crosslinked product, freeze-drying, soaking in antibacterial agent solution to absorb antibacterial agent, and freeze-drying.