▎ 摘　　要

NOVELTY - Piezoelectric nano-particle BCG-NPs, is core-shell type piezoelectric nano-particle, which mainly comprises barium titanate (BaTiO3) load on surface as positive portion of the chitosan, and load chitosan the surface as negative electric portion of graphene oxidation. USE - Piezoelectric nano-particle BCG-NPs. ADVANTAGE - The piezoelectric nano-particle significantly improves dispersion performance, have a wide range of applications in medicine, such as modifying various implant materials, carrying drugs as nanocapsules, antibacterial, osteogenesis, and inhibition through various mechanisms tumors and more, which requires that the nanoparticles have good dispersion properties to maintain the nanometer size, which is the basis for the nanoparticles to have a large specific surface area and exert a small size effect. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for: A method for preparing piezoelectric nanoparticles BCG-NPs, which involves: adding BaTiO3 powder into water and ultrasonically dispersing, then slowly dropping 2-4 wt.% chitosan acetic acid solution into the BaTiO3 dispersion, after stirring for 4-6 hours, centrifuging mixture to remove unreacted reagents, and the precipitate is BC-NPs, further washing, drying; adding BC-NPs to water, ultrasonically dispersing, and slowly dropping into 2 wt.% graphene oxide aqueous solution, after stirring for 8-15 hours to form a suspension, then centrifuging, washing, and drying. A device for ultrasonic treatment of a patient implanted with bionic bone material, which comprises: (a) ultrasonic probes used to contact patients with diseased portions to stimulate bionic bone materials to generate microcurrents; (b) a control unit for controlling the ultrasonic conditions, preferably, the biomimetic bone material is the piezoelectric nanoparticle BCG-NPs.