• 专利标题:   Preparing biliary stent material contains coating layer used for treating tumor, involves pre-treating substrate, polishing, removing oil selected from sodium bicarbonate solution, selecting de-ionized water, auxiliary with ultrasonicating.
  • 专利号:   CN113730663-A, CN113730663-B
  • 发明人:   TAN Y, ZHAO J, YAO L, XIAO Y
  • 专利权人:   UNIV CENT SOUTH XIANGYA HOSPITAL
  • 国际专利分类:   A61L031/08, A61L031/10, A61L031/16
  • 专利详细信息:   CN113730663-A 03 Dec 2021 A61L-031/10 202210 Chinese
  • 申请详细信息:   CN113730663-A CN11039448 06 Sep 2021
  • 优先权号:   CN11039448

▎ 摘  要

NOVELTY - Preparing biliary stent material contains coating layer involves grinding and polishing substrate, polishing, removing oil, cleaning and drying, where oil is selected from sodium bicarbonate solution; selecting deionized water and auxiliary with ultrasonication and drying under condition of nitrogen; weighing polylactic acid and adding ethyl acetate solution to obtain coating solution; adding triclosan and adding to poly lactic acid solution, stirring uniformly to obtain coating solution; soaking pre-treated biliary substrate into coating liquid for 15-20 minutes, taking out and drying and then soaking again, repeating for 5-8 times, and drying in vacuum for 40-60 hours. USE - Method for preparing biliary stent material contains coating layer used for treating biliary tract obstruction caused by stone, inflammation, tumor and scar. ADVANTAGE - The method helps in improving antibacterial performance of biliary stent, and has good biological compatibility; avoids bacteria and protein material attached on surface of bracket, and reduces hemolysis rate of stent material to satisfactory level. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a biliary stent.