• 专利标题:   Optical fiber miRNA sensor based on the gold nanoparticle coated with graphene oxide for quantitative detection of RNA, comprises broadband light source, Y-shaped optical fiber, optical fiber probe, spectrometer.
  • 专利号:   CN115308144-A
  • 发明人:   ZENG S, LUO Z, PAN Z, DING L, XU B
  • 专利权人:   UNIV CHINA THREE GORGES
  • 国际专利分类:   C12N015/113, C12Q001/6806, C12Q001/6886, G01N021/01, G01N021/31
  • 专利详细信息:   CN115308144-A 08 Nov 2022 G01N-021/31 202304 Chinese
  • 申请详细信息:   CN115308144-A CN10872862 21 Jul 2022
  • 优先权号:   CN10872862

▎ 摘  要

NOVELTY - Optical fiber miRNA sensor based on the gold nanoparticle coated with graphene oxide, comprises broadband light source, Y-shaped optical fiber, optical fiber probe, spectrometer, where the sensing probe side is coated with graphene oxide-gold nano-RNA composite material (GO-AuNPs-RNA probe), the end of the optical fiber probe is coated with a reflective silver mirror; the light enters the optical fiber sensing probe through the Y-shaped optical fiber, and excites the graphene oxide-gold nano-sensitive material on the side of the probe to generate a localized surface plasmon resonance. USE - The sensor and the probe are useful for quantitative detection of RNA (claimed). ADVANTAGE - The sensor overcomes the disadvantages of traditional method, expensive and, lays the foundation for application of optical fibre LSPR sensor in the field of biomedicine diagnosis. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for optical fibre probe sensitive material.