▎ 摘　　要

NOVELTY - A nickel-metal organic framework-based electrochemical sensor comprises glassy carbon electrode, where the glassy carbon electrode is wrapped with a composite material nickel-metal organic framework-74-graphene oxide-platinum nanoparticles, and the composite material is processed by dissolving nickel nitrate hexahydrate in a solvent and fully dissolving to form a mixed solution-A, dissolving 2,5-dihydroxyterephthalic acid in a solvent to form a mixed solution-B, ultrasonically dispersing a graphite oxide in a solvent until a homogeneous solution to obtain graphene solution-C, mixing the solutions of A, B, C and stirring, mixing, heating, cooling, centrifuging, washing and drying, ultrasonically dispersing nickel-metal organic framework-74-graphene oxide and potassium chloroplatinate in methanol solution, mixing, adding sodium borohydride methanol solution, stirring, centrifuging and drying to obtain nickel-metal organic framework-74-graphene oxide-platinum nanoparticle composite. USE - Nickel-metal organic framework-based electrochemical sensor. ADVANTAGE - The nickel-metal organic framework-based electrochemical sensor can be prepared with strong anti-interference ability, and effectively detecting the uric acid in human serum in rapid manner. DETAILED DESCRIPTION - A nickel-metal organic framework-based electrochemical sensor comprises glassy carbon electrode, where the glassy carbon electrode is wrapped with a composite material nickel-metal organic framework-74-graphene oxide-platinum nanoparticles, and the composite material is processed by dissolving nickel nitrate hexahydrate in a solvent and fully dissolving to form a mixed solution-A, dissolving 2,5-dihydroxyterephthalic acid in a solvent to form a mixed solution-B, ultrasonically dispersing a graphite oxide in a solvent until a homogeneous solution to obtain graphene solution-C, mixing the solutions of A, B, C and stirring for 30 minutes, uniformly mixing, placing in a reaction kettle and heating to 100 degrees C for 24 hours, cooling to room temperature, centrifuging, washing with dimethyl formamide and drying under vacuum to obtain the nickel-metal organic framework-74-graphene oxide composite, ultrasonically dispersing nickel-metal organic framework-74-graphene oxide and potassium chloroplatinate in methanol solution, mixing and dispersing uniformly, adding a certain amount of sodium borohydride methanol solution, stirring for 2 hours, centrifuging, washing with methanol for three times and vacuum drying to obtain nickel-metal organic framework-74-graphene oxide-platinum nanoparticle composite.