▎ 摘　　要

NOVELTY - A substrate is immersed in a graphene oxide aqueous suspension to obtain a graphene-oxide-immobilized substrate, which is then washed, dried and heated. The prepared substrate is immersed in aminated multiwalled carbon nanotube suspension and the carbon nanotubes are deposited to obtain graphene oxide/multiwalled carbon nanotube bilayer thin-film substrate, which is washed, dried and heated. The substrate is immersed in hydrazine hydrate solution for reduction, washed, and dried to obtain graphene oxide/multiwalled carbon nanotube film-based substrate. USE - Manufacture of graphene oxide/multiwalled carbon nanotube film-based substrate used in laser desorption ionization-mass spectrometry detection of hydrophobic molecules, and ion mobility spectrometry (all claimed). ADVANTAGE - The method enables manufacture of graphene oxide/multiwalled carbon nanotube film-based substrates which enable detection of small molecules.