• 专利标题:   Assembling screen-printed electrodes used for detecting thyroid stimulating hormone (TSH) by interacting graphene oxide electrochemically functionalized with polydiphenylamine/1,4-phenylene diisothiocyanate/G protein electrode with TSH antibody solution, and incubating in TSH antigen solution.
  • 专利号:   RO135945-A2
  • 发明人:   FEJER S, BAIBARAC M
  • 专利权人:   PROVITAM SRL, INST NAT CERCETARE DEZV FIZICA MATERIALE
  • 国际专利分类:   G01N027/26, G01N033/53
  • 专利详细信息:   RO135945-A2 30 Aug 2022 G01N-027/26 202284 Pages: 1 English
  • 申请详细信息:   RO135945-A2 RO000028 02 Feb 2021
  • 优先权号:   RO000028

▎ 摘  要

NOVELTY - Chemical process for assembling screen-printed electrodes for detection of thyroid stimulating hormone (TSH) involves synthesizing screen-printed electrodes modified with graphene oxide electrochemically functionalized with polydiphenylamine (GO/PDPA), chemically interacting with 1,4-phenylene diisothiocyanate (PDITC), obtaining product GO/PDPA/PDITC, chemically interacting with G protein that leads to covalent attachment of G protein to electrode surface, interacting GO/PDPA/PDITC/G electrode with a TSH antibody solution and incubating in TSH antigen solution at a pH of 7.4 for 1 hour, and obtaining an assembled GO/PDPA/PDITC/G/TSH/TSH antibody structure. USE - The chemical process is useful for assembling screen-printed electrodes for detecting TSH.